Evidence map›Paper›PMID 32922366›Full record

SynthesisFrontiers in endocrinology2020

Body Mass Index and Prognosis of COVID-19 Infection. A Systematic Review.

Karina Colombera Peres, Rachel Riera, Ana Luiza Cabrera Martimbianco, Laura Sterian Ward, Lucas Leite Cunha

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Recent Advance Analysis of Recovery in Hospitalized People with COVID-19: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
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  9. COVID-19 lockdown consequences on body mass index and perceived fragility related to physical activity: A worldwide cohort study.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
  10. Article
  11. Association of Patient Characteristics, Diabetes, BMI, and Obesity With Severe COVID-19 in Metropolitan Detroit, MI.Clinical diabetes : a publication of the American Diabetes Association · 2022
    Article
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  16. A Clinical Monitoring Program of COVID-19 Outpatients: A Prospective Cohort Study.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karina Colombera PeresLaboratory of Cancer Molecular Genetics, School of Medical Sciences, University of Campinas, Campinas, Brazil.
Rachel RieraDiscipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Ana Luiza Cabrera MartimbiancoPostgraduate Program in Health and Environment, Universidade Metropolitana de Santos, São Paulo, Brazil.
Laura Sterian WardLaboratory of Cancer Molecular Genetics, School of Medical Sciences, University of Campinas, Campinas, Brazil.
Lucas Leite CunhaLaboratory of Cancer Molecular Genetics, School of Medical Sciences, University of Campinas, Campinas, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A better understanding of the SARS-CoV-2 virus behavior and possible risk factors implicated in poor outcome has become an urgent need. We performed a systematic review in order to investigate a possible association between body weight and prognosis among patients diagnosed with COVID-19. We searched in Cochrane Library, EMBASE, MEDLINE, WHO-Global Literature on Coronavirus Disease, OpenGrey, and Medrxiv. We used the ROBINS-I tool or Cross-Sectional/Prevalence Study Quality tool from AHRQ, to evaluate the methodological quality of included studies. Nine studies (two prospective cohorts, four retrospective cohorts and three cross-sectional) were included and assessed the relationship between obesity and COVID-19 prognosis. Risk of bias of the included studies ranged from moderate to critical. Clinical and methodological heterogeneity among them precluded meta-analyses. Most of the included studies showed some degree of association to: (a) higher BMI and worse clinical presentation and (b) obesity and need of hospitalization. The results were inconsistent about the impact of obesity on mortality. Based on limited methodological quality studies, obesity seems to predict poor clinical evolution in patients with COVID-19. Further studies with appropriate prospective design are needed to reduce the uncertainty on this evidence.

Indexed as

Body Mass IndexBetacoronavirusCohort StudiesCoronavirus InfectionsCOVID-19HumansObesityPandemicsPneumonia, ViralPrognosisSARS-CoV-2Survival Ratebody mass indexCOVID-19obesityrisk factorSARS-CoV-2

Identifiers

PMID32922366
PMCPMC7456965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.