Evidence map›Paper›PMID 32922309›Full record

ArticleFrontiers in physiology2020

Suppression of Connexin 43 Leads to Strial Vascular Hyper-Permeability, Decrease in Endocochlear Potential, and Mild Hearing Loss.

Jinhui Zhang, Xiaohan Wang, Zhiqiang Hou, Lingling Neng, Jing Cai, Yunpei Zhang, Xiaorui Shi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. A Systematic Review of Genes Affecting Endocochlear Potential.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Pooled it
  2. A Systematic Review on the Role of the Stria Vascularis in Menière's Disease Pathogenesis.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Pooled it
  3. Article
  4. Skin capillary endothelial cells form a network of spatiotemporally conserved CaProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  6. Review
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  12. Astrocytic responses to high glucose impair barrier formation in cerebral microvessel endothelial cells.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  13. Article
  14. AFrontiers in cell and developmental biology · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jinhui ZhangOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Xiaohan WangOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Zhiqiang HouOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Lingling NengOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Jing CaiOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Yunpei ZhangOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Xiaorui ShiOregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Oregon Health & Science University · USBoston Children's Hospital · US

Funding

PORTLAND AREA COMMUNICATION RESEARCH CORE CENTERP30DC005983 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI NUTTALL, ALFRED L · 2003 to 2017
$9.0M
The role of vascular endothelial growth factor signaling in normal hearing andaging-related cochlear atrophyR01DC018534 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Xiaorui Shi · 2020 to 2026
$2.6M
Strial vascular pathology from acoustic traumaR01DC015781 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHI, XIAORUI · 2017 to 2021
$2.0M
Fibrovascular coupling in the cochlea and pericyte recruitment after noiseR01DC010844 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHI, XIAORUI · 2010 to 2014
$1.9M
Cochlear angiogenesisR21DC016157 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHI, XIAORUI · 2017 to 2018
$516k
NIDCD NIH HHS P30 DC005983NIDCD NIH HHS R01 DC010844NIDCD NIH HHS R01 DC015781NIDCD NIH HHS R01 DC018534NIDCD NIH HHS R21 DC016157
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blood-labyrinth-barrierconnexin 43endocochlear potentialhearing lossmouseperivascular macrophage

Identifiers

PMID32922309
PMCPMC7457066
OpenAlexW3049428973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.