ArticleFrontiers in physiology2020
Effects of Mechanical Dyssynchrony on Coronary Flow: Insights From a Computational Model of Coupled Coronary Perfusion With Systemic Circulation.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Acute effects of mechanical dyssynchrony on left ventricular function and coronary perfusion.Frontiers in bioengineering and biotechnology · 2025Article
- Comparison of Left Ventricular Function Derived from Subject-Specific Inverse Finite Element Modeling Based on 3D ECHO and Magnetic Resonance Images.Bioengineering (Basel, Switzerland) · 2024Article
- Simulation of coronary capillary transit time based on full vascular model of the heart.Computer methods and programs in biomedicine · 2024Article
- Preconditioning with selective autoretroperfusion:Frontiers in bioengineering and biotechnology · 2024Article
- Mechanism of exercise intolerance in heart diseases predicted by a computer model of myocardial demand-supply feedback system.Computer methods and programs in biomedicine · 2022Article
- Optimization of cardiac resynchronization therapy based on a cardiac electromechanics-perfusion computational model.Computers in biology and medicine · 2022Article
- A Closed-Loop Modeling Framework for Cardiac-to-Coronary Coupling.Frontiers in physiology · 2022Article
- Role of Electromechanical Dyssynchrony Assessment During Acute Circulatory Failure and Its Relation to Ventriculo-Arterial Coupling.Frontiers in cardiovascular medicine · 2022Article
- Role of coronary flow regulation and cardiac-coronary coupling in mechanical dyssynchrony associated with right ventricular pacing.American journal of physiology. Heart and circulatory physiology · 2021Article
- The Comparison of Different Constitutive Laws and Fiber Architectures for the Aortic Valve on Fluid-Structure Interaction Simulation.Frontiers in physiology · 2021Article
- Transmural Distribution of Coronary Perfusion and Myocardial Work Density Due to Alterations in Ventricular Loading, Geometry and Contractility.Frontiers in physiology · 2021Article
- Review of cardiac-coronary interaction and insights from mathematical modeling.WIREs mechanisms of diseaseReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanical dyssynchrony affects left ventricular (LV) mechanics and coronary perfusion. Due to the confounding effects of their bi-directional interactions, the mechanisms behind these changes are difficult to isolate from experimental and clinical studies alone. Here, we develop and calibrate a closed-loop computational model that couples the systemic circulation, LV mechanics, and coronary perfusion. The model is applied to simulate the impact of mechanical dyssynchrony on coronary flow in the left anterior descending artery (LAD) and left circumflex artery (LCX) territories caused by regional alterations in perfusion pressure and intramyocardial pressure (
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Registered trials
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