Evidence map›Paper›PMID 32922198›Full record

ArticleInternational journal of medical sciences2020

Downregulation of Cypher induces apoptosis in cardiomyocytes via Akt/p38 MAPK signaling pathway.

Tianming Xuan, Dongfei Wang, Jialan Lv, Zhicheng Pan, Juan Fang, Yin Xiang, Hongqiang Cheng, Xingxiang Wang, Xiaogang Guo

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  9. Article
  10. Understanding the molecular basis of cardiomyopathy.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tianming XuanDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Dongfei WangDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jialan LvDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhicheng PanDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Juan FangDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yin XiangDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hongqiang ChengDepartment of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China.
Xingxiang WangDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiaogang GuoDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
First Affiliated Hospital Zhejiang University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetatesAdaptor Proteins, Signal TransducingAnimalsAnimals, NewbornApoptosisBenzopyransCardiomyopathy, DilatedCell SurvivalDisease Models, AnimalDown-RegulationGene Knockdown TechniquesHEK293 CellsHumansLIM Domain ProteinsMAP Kinase Signaling SystemMiceAcetatesAdaptor Proteins, Signal TransducingAKT activator SC79BenzopyransLdb3 protein, mouseLdb3 protein, ratLIM Domain Proteinsp38 Mitogen-Activated Protein KinasesProto-Oncogene Proteins c-aktAktapoptosisCypherdilated cardiomyopathyp38 MAPK

Identifiers

PMID32922198
PMCPMC7484636
OpenAlexW3083866716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.