Evidence map›Paper›PMID 32922183›Full record

ArticleInternational journal of medical sciences2020

2,3,5,4'-tetrahydoxystilbene-2-O-β-D-glucoside eliminates staurosporine-induced cytotoxicity by restoring BDNF-TrkB/Akt signaling axis.

Teng-Teng Ren, Sheng-Rui Fan, Xiu-Yuan Lang, Yun Yu, Rongfeng Lan, Xiao-Yan Qin

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Effect of retinoic acid on delayed encephalopathy after acute carbon monoxide poisoning: Role of the lncRNAZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  2. Article
  3. Preclinical Evidence and Underlying Mechanisms ofJournal of pharmacopuncture · 2024
    Review
  4. Article
  5. Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Teng-Teng RenCenter on Translational Neuroscience, College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Sheng-Rui FanCenter on Translational Neuroscience, College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Xiu-Yuan LangCenter on Translational Neuroscience, College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Yun YuCenter on Translational Neuroscience, College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Rongfeng LanDepartment of Cell Biology & Medical Genetics, School of Basic Medical Sciences, Shenzhen University Health Science Center, Shenzhen 518060, China.
Xiao-Yan QinCenter on Translational Neuroscience, College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Minzu University of China · CNShenzhen University Health Science Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside (THSG) is the major active ingredient in

Indexed as

AnimalsAnimals, NewbornApoptosisBrain-Derived Neurotrophic FactorCarbazolesCells, CulturedCell SurvivalChromonesFallopia multifloraGlucosidesHippocampusIndole AlkaloidsMorpholinesNeuronsNeuroprotective AgentsPrimary Cell Culture2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneAkt1 protein, ratBdnf protein, ratBrain-Derived Neurotrophic FactorCarbazolesChromonesGlucosidesIndole AlkaloidsMorpholinesNeuroprotective AgentsNtrk2 protein, ratProto-Oncogene Proteins c-aktReceptor, trkBStaurosporinestaurosporine aglyconeStilbenesAktBDNFK252aLY294002staurosporineTHSGTrkB

Identifiers

PMID32922183
PMCPMC7484659
OpenAlexW3084323749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.