Evidence map›Paper›PMID 32921784›Full record

SynthesisActa bio-medica : Atenei Parmensis2020

Prevalence of Parkinson Disease in Italy: a systematic review and meta-analysis.

Matteo Riccò, Luigi Vezzosi, Federica Balzarini, Giovanni Gualerzi, Silvia Ranzieri, Carlo Signorelli, Maria Eugenia Colucci, Nicola Luigi Bragazzi

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Contrast Sensitivity Function in Parkinson's Disease: Effects of Illumination and Disease Stage.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Update: Descriptive epidemiology of Parkinson disease.Parkinsonism & related disorders · 2024
    Review
  11. Article
  12. What is the Parkinson Pandemic?Movement disorders : official journal of the Movement Disorder Society · 2023
    Article
  13. Article
  14. Review
  15. Gender Differences in the Prevalence of Parkinson's Disease.Movement disorders clinical practice · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Mortality of Parkinson's disease in Italy from 1980 to 2015.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  20. Burden of Parkinson's disease in Sicily: a health administrative database study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo RiccòAzienda USL di Reggio EmiliaV.le Amendola n.2 - 42122 REServizio di Prevenzione e Sicurezza negli Ambienti di Lavoro (SPSAL)Dip. di Prevenzione. mricco2000@gmail.com.
Luigi VezzosiAgenzia di Tutela della Salute (ATS) della Val Padana; Via Toscani n.1; Mantova (MN), Italy. luigi_vezzosi@yahoo.it.
Federica BalzariniUniversity "Vita e Salute", San Raffaele Hospital; Via Olgettina n. 58, 20132; Milan (MI), Italy. federica.balzarini@gmail.com.
Giovanni GualerziUniversity of Parma, Department of Medicine and Surgery, School of Medicine; Via Gramsci n.14, 43123; Parma (PR), Italy. gualerzi@gmail.com.
Silvia RanzieriUniversity of Parma, Department of Medicine and Surgery, School of Occupational Medicine; Via Gramsci n.14, 43123; Parma (PR), Italy. silvia.ranzieri@studenti.unipr.it.
Carlo SignorelliUniversity "Vita e Salute", San Raffaele Hospital; Via Olgettina n. 58, 20132; Milan (MI), Italy. signorelli.carlo@hsr.it.
Maria Eugenia ColucciUniversity of Parma, Department of Medicine and Surgery, School of Hygiene and Public Health; Via Gramsci n.14, 43123; Parma (PR), Italy. mariaeugenia.colucci@unipr.it.
Nicola Luigi BragazziLaboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, University of York, Toronto (ON), Canada. dottornicolaluigibragazzi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionParkinson's disease (PD) is a common disease of unknown etiology. Even though accurate information on the epidemiology of PD is critical for defining appropriate health policies, epidemiological data on Parkinson's disease (PD) in Italy are often defined as scant or conflicting. Our study attempted to provide an overview on the prevalence of (PD) by means of a systematic review and metanalysis of existing data.   Material and methods. We searched into two different databases (PubMed and EMBASE), focusing on studies reporting the prevalence of PD in Italy. Data were extracted using a standardized assessment form, and results of such analyses were systematically reported, summarized and compared.   Results. A total of 16 studies were eventually included in the analyses, with a prevalence rate of 193.7/100,000. Available reports were heterogeneous both in design and in eventual figures, and also prevalence estimates were affected by substantial heterogeneity. Interestingly, prevalence rates ranged from 37.8/100,000 inhabitants in subjects aged 0 to 64 years, to 578.7 in age group 65 to 75 years, and 1235.7 in age group 75 years or older. PD was significantly associated with male sex, but only in older age groups (i.e. Odds Ratio, OR 1.37 95%CI 1.22-1.53, and OR 1.31, 95%CI 1.21-1.42 for age groups 65-74 years and 75 years or more, respectively).   Discussion and conclusion. While the observed variations in prevalence rates may result from environmental or genetic factors, differences in methodologies for case ascertainment and diagnostic criteria may have significantly affected our estimates. As a consequence, the comparability of existing studies is limited.

Indexed as

Parkinson DiseaseAgedDatabases, FactualHealth PolicyHumansItalyMalePrevalence

Identifiers

PMID32921784
PMCPMC7717000

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.