Evidence map›Paper›PMID 32921753›Full record

ReviewActa bio-medica : Atenei Parmensis2020

Celiac disease and headache in children: a narrative state of the art.

Luca Sabino, Silvia Marino, Raffaele Falsaperla, Francesco Pisani, Carmen Massimino, Piero Pavone

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luca SabinoPediatric and Pediatric Emergency Department, University Hospital "Policlinico-Vittorio Emanuele" and cPediatric Clinic, Department of Clinical and Experimental Medicine, University Hospital "Policlinico-Vittorio Emanuele", Catania, Italy. luca.sabino94@gmail.com.
Silvia MarinoaPediatric and Pediatric Emergency Department, University Hospital "Policlinico-Vittorio Emanuele", Catania, Italy;. silvia_marino86@hotmail.it.
Raffaele FalsaperlaaPediatric and Pediatric Emergency Department, University Hospital "Policlinico-Vittorio Emanuele", Catania, Italy. raffaelefalsaperla@hotmail.com.
Francesco PisaniChild Neuropsychiatric Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy. francesco.pisani@unipr.it.
Carmen MassiminocPediatric Clinic, Department of Clinical and Experimental Medicine, University Hospital "Policlinico-Vittorio Emanuele", Catania, Italy. ppavone@unict.it.
Piero PavonePediatric Clinic, Department of Clinical and Experimental Medicine, University Hospital "Policlinico-Vittorio Emanuele", Catania, Italy. ppavone@unict.it.
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is one of the most important entity of the wide spectrum of gluten-related disorders (GRDs). It is well known that neurological manifestation can be present either at the onset of CD, or appear during the development of the pathology, and different can be the neurologic findings. Clinical features are very variable, ranging from typical manifestations of gastrointestinal involvement to neurologic symptom. The most frequent neurologic signs reported were headache, epileptic seizure, migraine, mental retardation, ataxia and attention deficit and hyperactive disorder. Headache either in form of migraine, or in non-specific form represents one of the main clinical presentation in CD. The aim of this work is to provide a narrative review of the pediatric literature focused on the cephalalgic features of children with CD evaluating the potential benefits of a gluten free diet (GFD).  Papers were identified by searching for related literature in Medline (PubMed) and Embase using the words "Celiac Disease" and "Headache" or "Migraine" by specifying "children"/"paediatric age" for reports published since 1972 till 31th October 2018. According to our inclusion criteria, a total of 25 papers has been evaluated. Although it is still controversial if headache is prevalent in CD children a correct compliance to a GFD seems to improve the neurological symptoms even if the underlying pathogenic relationship between CD and neurologic system involvement is still not fully understood.

Indexed as

Celiac DiseaseEpilepsyChildDiet, Gluten-FreeGlutensHeadacheHumansGlutens

Identifiers

PMID32921753
PMCPMC7717030
OpenAlexW3084461405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.