Evidence map›Paper›PMID 32921726›Full record

ReviewActa bio-medica : Atenei Parmensis2020

Coronavirus infections in children: from SARS and MERS to COVID-19, a narrative review of epidemiological and clinical features.

Rosanna Iannarella, Claudia Lattanzi, Giulia Cannata, Alberto Argentiero, Cosimo Neglia, Valentina Fainardi, Giovanna Pisi, Susanna Esposito

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Recent Advances in Antiviral Activities of Triterpenoids.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  12. Understanding Kids and COVID.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. [Seroprevalence of SARS-CoV-2 among children and adolescents in Germany-an overview].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2021
    Review
  14. Coronavirus Disease 2019 in Children.Frontiers in pediatrics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Rosanna IannarellaPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. rosanna.iannarella@hotmail.it.
Claudia LattanziPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. claudial1992@gmail.com.
Giulia CannataPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. cannata.giulia@gmail.com.
Alberto ArgentieroPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. aargentiero85@gmail.com.
Cosimo NegliaPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. cosimo.neglia@unipr.it.
Valentina FainardiPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. valentina.fainardi@gmail.com.
Giovanna PisiPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. gpisi@ao.pr.it.
Susanna EspositoPediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma. susannamariaroberta.esposito@unipr.it.
Regional Children's Clinical Hospital No. 1 · RUUniversity of Parma · ITBarilla (Italy) · ITOspedale di Parma · ITRetina Clinic · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging and re-emerging viruses represent an important challenge for global public health. In the 1960s, coronaviruses (CoVs) were recognized as disease agents in humans. In only two decades, three strains of CoVs have crossed species barriers rapidly emerging as human pathogens resulting in life-threatening disease with a pandemic potential: severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, Middle-East respiratory syndrome coronavirus (MERS-CoV) in 2012 and the recently emerged SARS-CoV-2. This narrative review aims to provide a comprehensive overview of epidemiological, pathogenic and clinical features, along with diagnosis and treatment, of the ongoing epidemic of new coronavirus disease 2019 (COVID-19) in the pediatric population in comparison to the first two previous deadly coronavirus outbreaks, SARS and MERS. Literature analysis showed that SARS-CoV, MERS-CoV and SARS-CoV-2 infections seem to affect children less commonly and less severely as compared with adults. Since children are usually asymptomatic, they are often not tested, leading to an underestimate of the true numbers infected. Most of the documented infections belong to family clusters, so the importance of children in transmitting the virus remains uncertain. Like in SARS and MERS infection, there is the possibility that children are not an important reservoir for novel CoVs and this may have important implications for school attendance. While waiting for an effective against SARS-CoV-2, further prevalence studies in paediatric age are needed, in order to clarify the role of children in different age groups in the spread of the infection.

Indexed as

BetacoronavirusMiddle East Respiratory Syndrome CoronavirusPandemicsChildCoronavirus InfectionsCOVID-19HumansIncidencePneumonia, ViralSARS-CoV-2Severe Acute Respiratory Syndrome

Identifiers

PMID32921726
PMCPMC7716978
OpenAlexW3086750450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.