SynthesisActa bio-medica : Atenei Parmensis2020
SARS-CoV-2 recurrent RNA positivity after recovering from coronavirus disease 2019 (COVID-19): a meta-analysis.
Synthesis in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Global prevalence of coronavirus disease 2019 reinfection: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Reinfection rates among patients previously infected by SARS-CoV-2: systematic review and meta-analysis.Chinese medical journal · 2022Pooled it
- A systematic review on the recurrence of SARS-CoV-2 virus: frequency, risk factors, and possible explanations.Infectious diseases (London, England) · 2021Pooled it
- Recurrent SARS-CoV-2 infections and their potential risk to public health - a systematic review.PloS one · 2021Pooled it
- Clinical features and corresponding immune function status of recurrent viral polymerase chain reaction positivity in patients with COVID-19 : A meta- analysis and systematic review.International journal of immunopathology and pharmacologyPooled it
- Clinical characteristics associated with recurrent viral RNA positivity in patients within two weeks after recovering from the first SARS-CoV-2 infection.Biomolecules & biomedicine · 2024Article
- Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing.Scientific reports · 2023Article
- Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities.PLoS pathogens · 2023Review
- SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19.International journal of molecular sciences · 2022Review
- What we need for COVID-19 post-acute care.European geriatric medicine · 2022Article
- Milder symptoms and shorter course in patients with re-positive COVID-19: A cohort of 180 patients from Northeast China.Frontiers in microbiology · 2022Article
- Solid Organ Transplantation in SARS-CoV-2 Recovered Transplant Candidates: a Comprehensive Review of Recent Literature.Current transplantation reports · 2022Review
- Anti-SARS-CoV-2 antibody immunoreactivity profiles during COVID-19 recurrence.Revista da Sociedade Brasileira de Medicina Tropical · 2022Article
- SARS-CoV-2 reinfection: "New baseline" imaging concept in the era of COVID-19.Clinical imaging · 2021Article
- Clinical characteristics of re-hospitalized COVID-19 patients with recurrent positive SARS-CoV-2 RNA: a retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- A systematic review and meta-analysis of discharged COVID-19 patients retesting positive for RT-PCR.EClinicalMedicine · 2021Article
- A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh.Tropical medicine and infectious disease · 2021Article
- COVID-19 reinfection: the role of natural immunity, vaccines, and variants.Journal of community hospital internal medicine perspectives · 2021Review
- Retest positive for SARS-CoV-2 RNA in pregnant women recovered from COVID-19.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2020Article
- Learning from SARS and MERS: COVID-19 reinfection where do we stand?Travel medicine and infectious diseaseArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimIsolation of subjects with active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a pivotal preventive measure in the ongoing coronavirus disease 2019 (COVID-19) pandemic. A growing number of studies reported cases of recurrent SARS-CoV-2 RNA positivity following disease recovery, which were identified with a critical literature search and then meta-analyzed in this article. MATERIALS AND
methodsA digital search was performed in Medline and Web of Science, using the keywords "coronavirus disease 2019" OR "COVID-19" OR "severe acute respiratory disease 2" OR "SARS-CoV-2" AND "recurrence" OR "repositivization" OR "retesting", without date or language restrictions. Recovery was defined as resolution of symptoms, with at least two consecutive negative molecular tests.
resultsA total number of 17 studies, with 5,182 COVID-19 patients, were included. SARS-CoV-2 recurrent RNA positivity in recovered COVID-19 patients ranged between 7-23% across the studies, with follow-up testing between 1-60 days. The estimated cumulative rate of SARS-CoV-2 recurrent RNA positivity was 12% (95% confidence interval, 12-13%; I2, 74%).
conclusionsRepeated molecular testing on respiratory tracts specimens at 1 and 2 months after recovery from COVID-19 is strongly advisable for early identification, isolation and clinical management of subjects with SARS-CoV-2 recurrent RNA positivity.
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