ReviewNeurosurgery clinics of North America2020
Leptomeningeal Carcinomatosis: Molecular Landscape, Current Management, and Emerging Therapies.
Review in Neurosurgery clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis.Journal of neuro-oncology · 2023Pooled it
- Leptomeningeal disease (LMD) after resection of brain metastases: results of the multicenter SUBAROMA study.Journal of neuro-oncology · 2026Article
- How is rosette formation in brain tumours linked with cerebrospinal fluid spread?Brain tumor pathology · 2026Review
- Leptomeningeal carcinomatosis in gastric cancer: a single-center retrospective analysis of 86 cases.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- Leptomeningeal metastasis from colon cancer: a case report and review of literature.Frontiers in oncology · 2026Article
- Isolated Leptomeningeal Carcinomatosis in Urothelial Carcinoma: A Case Report of Positive CSF Cytology With Negative Imaging.Case reports in oncological medicine · 2025Article
- Article
- Repurposing mebendazole against triple-negative breast cancer CNS metastasis.Journal of neuro-oncology · 2024Article
- Neurologic pathologies of the vertebral spine.Skeletal radiology · 2024Review
- Review
- A non-enhancing, T2 fluid-attenuated inversion recovery hyperintense, diffusion-restricting brainstem lesion in an EGFR tyrosine kinase inhibitor-treated non-small-cell lung cancer patient.Biomarkers in medicine · 2024Article
- Article
- Diagnostic and Therapeutic Updates in Leptomeningeal Disease.Current oncology reports · 2023Review
- GM-CSF - an oncogenic driver of HER2+ breast leptomeningeal metastasis.Oncoscience · 2022Article
- Case Report: Focal leptomeningeal disease, atypical cancer of unknown primary site.F1000Research · 2022Article
- Stroke secondary to leptomeningeal carcinomatosis with radiologic signs of arterial invasion.Surgical neurology international · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Leptomeningeal carcinomatosis is a devastating consequence of late-stage cancer, and despite multimodal treatment, remains rapidly fatal. Definitive diagnosis requires identification of malignant cells in the cerebrospinal fluid (CSF), or frank disease on MRI. Therapy is generally palliative and consists primarily of radiotherapy and/or chemotherapy, which is administered intrathecally or systemically. Immunotherapies and novel experimental therapies have emerged as promising options for decreasing patient morbidity and mortality. In this review, the authors discuss a refined view of the molecular pathophysiology of leptomeningeal carcinomatosis, current approaches to disease management, and emerging therapies.
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