Evidence map›Paper›PMID 32921300›Full record

ArticleJournal of medical case reports2020

Neuroendocrine appendiceal tumor and endometriosis of the appendix: a case report.

Rogério Serafim Parra, Marley Ribeiro Feitosa, Giovana Bachega Badiale Biagi, Daniel Ferracioli Brandão, Margarida Maria Fernandes da Silva Moraes, Liliane Silvestre, José Vitor Cabral Zanardi, Nelson Hitamo Sato Junior, Omar Féres, José Joaquim Ribeiro da Rocha

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Appendiceal endometrioma mimicking appendiceal neoplasm.Journal of surgical case reports · 2025
    Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Postoperative Complications and Stoma Rates After Laparoscopic Resection of Deep Infiltrating Endometriosis with Bowel Involvement.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rogério Serafim ParraProctogastroclinic, Eliseu Guilherme St, 09, Ribeirão Preto, SP, Brazil. rsparra@hcrp.usp.br.ORCID https://orcid.org/0000-0002-5566-9284
Marley Ribeiro FeitosaProctogastroclinic, Eliseu Guilherme St, 09, Ribeirão Preto, SP, Brazil.
Giovana Bachega Badiale BiagiM&M Laboratory of Pathology and Cytology, Ribeirão Preto, SP, Brazil.
Daniel Ferracioli BrandãoM&M Laboratory of Pathology and Cytology, Ribeirão Preto, SP, Brazil.
Margarida Maria Fernandes da Silva MoraesM&M Laboratory of Pathology and Cytology, Ribeirão Preto, SP, Brazil.
Liliane SilvestreNucleus - Diagnostic Medicine, SP, Ribeirão Preto, Brazil.
José Vitor Cabral ZanardiFecunditá Clinic, Ribeirão Preto, SP, Brazil.
Nelson Hitamo Sato JuniorFecunditá Clinic, Ribeirão Preto, SP, Brazil.
Omar FéresProctogastroclinic, Eliseu Guilherme St, 09, Ribeirão Preto, SP, Brazil.
José Joaquim Ribeiro da RochaProctogastroclinic, Eliseu Guilherme St, 09, Ribeirão Preto, SP, Brazil.
Clinics Hospital of Ribeirão Preto · BRUniversidade de São Paulo · BRUniversidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEndometriosis of the appendix is very uncommon, accounting for only about 1% of all cases of endometriosis. However, endometriosis is found in the appendix in approximately 8-13% of patients with deep infiltrating endometriosis and is particularly common in patients with severe forms of deep infiltrating endometriosis. Neuroendocrine tumors are the most common neoplasms of the appendix and may be misdiagnosed when there are multiple endometriosis lesions in the pelvis. CASE PRESENTATION: We describe a case of a Caucasian patient with deep infiltrating endometriosis with rectal involvement, retrocervical lesions, and a right ovarian endometrioma with no suspected lesions in the appendix. She underwent laparoscopy and, after a systematic intraoperative evaluation, suspected involvement of the appendix was observed. The patient underwent ovarian cystectomy, excision of the pelvic endometriosis lesions, appendectomy, and anterior stapler discoid resection. Histopathological analysis of the appendix revealed endometriosis and a well-differentiated neuroendocrine carcinoma at the appendix tip. DISCUSSION: Our patient's case emphasizes the need to approach these lesions carefully and strengthens the indication for appendectomy when the appendix is affected in the setting of endometriosis. Despite the more likely diagnosis of appendiceal endometriosis, neuroendocrine tumors cannot be ruled out by imaging examinations, and both conditions can occur in the same patient.

Indexed as

Appendiceal NeoplasmsAppendixEndometriosisNeuroendocrine TumorsAppendectomyFemaleHumansAppendiceal neoplasmAppendixDeep infiltrating endometriosisEndometriosisNeuroendocrine tumor

Identifiers

PMID32921300
PMCPMC7489048
OpenAlexW3086793718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.