Evidence map›Paper›PMID 32920677›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021

Predictors for quality of life improvement after acute osteoporotic vertebral fracture: results of post hoc analysis of a prospective randomized study.

Hiroyuki Inose, Tsuyoshi Kato, Hiroaki Nakamura, Masatoshi Hoshino, Daisuke Togawa, Toru Hirano, Yasuaki Tokuhashi, Tetsuro Ohba, Hirotaka Haro, Takashi Tsuji and 10 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Improved radiological diagnosis of osteoporotic vertebral fragility fractures following UK-wide interventions and re-audit-can this be maintained and translated into clinical practice?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Hiroyuki InoseDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan. inose.orth@tmd.ac.jp.ORCID http://orcid.org/0000-0003-4195-2545
Tsuyoshi KatoDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan.
Hiroaki NakamuraDepartment of Orthopedic Surgery, Graduate School of Medicine, Osaka City University, Osaka, 545-8585, Japan.
Masatoshi HoshinoDepartment of Orthopedic Surgery, Graduate School of Medicine, Osaka City University, Osaka, 545-8585, Japan.
Daisuke TogawaDepartment of Orthopaedic Surgery, Hamamatsu University of Medicine, Shizuoka, 431-3192, Japan.
Toru HiranoDepartment of Orthopedic Surgery, Niigata University Medical and Dental Hospital, Niigata, 951-8520, Japan.
Yasuaki TokuhashiDepartment of Orthopaedic Surgery, Nihon University, Tokyo, 173-8610, Japan.
Tetsuro OhbaDepartment of Orthopaedic Surgery, University of Yamanashi, Yamanashi, 409-3898, Japan.
Hirotaka HaroDepartment of Orthopaedic Surgery, University of Yamanashi, Yamanashi, 409-3898, Japan.
Takashi TsujiDepartment of Orthopaedic Surgery, Kitasato University Kitasato Institute Hospital, Tokyo, 108-8642, Japan.
Kimiaki SatoDepartment of Orthopaedic Surgery, Kurume University School of Medicine, Kurume University, Fukuoka, 830-0011, Japan.
Yutaka SasaoDepartment of Orthopaedic Surgery, Graduate School, School of Medicine, St. Marianna University, Kanagawa, 216-8511, Japan.
Masahiko TakahataDepartment of Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Hokkaido, 060-8638, Japan.
Koji OtaniDepartment of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan.
Suketaka MomoshimaDepartment of Diagnostic Radiology, Center for Preventive Medicine, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Kunihiko TakahashiDepartment of Biostatistics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan.
Masato YuasaDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan.
Takashi HiraiDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan.
Toshitaka YoshiiDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan.
Atsushi OkawaDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan.

Funding

Japan Agency for Medical Research and Development 16dk0110008h0003
6 · The paper itself

Abstract

purposeNo study has investigated the clinical and radiographic risk factors for the deterioration of quality of life (QOL) beyond 6 months after osteoporotic vertebral fractures (OVF). The purpose of this study was to identify the predictors associated with poor QOL improvement after OVF.

methodsThis post hoc analysis included 166 women aged 65-85 years with acute 1-level OVFs. For the patient-reported outcome measures, scores on the European Quality of Life-5 Dimensions (EQ-5D) scale, and visual analogue scale (VAS) for low back pain were used. Lateral radiography at 0, 12, and 48 weeks and magnetic resonance imaging (MRI) at enrollment and at 48 weeks were performed. The associations between baseline variables with change scores for EQ-5D were investigated using a multiple linear regression model.

resultsUnivariate analysis showed that time since fracture, EQ-5D score, and VAS for low back pain at 0 week showed significant association with increased EQ-5D score from 0 to 48 weeks. According to the multiple regression analysis, the following equation was obtained: increased EQ-5D score from 0 to 48 weeks = 1.305 - 0.978 × EQ-5D at 0 week - 0.021 × VAS for low back pain at 0 week - 0.006 × age + (fluid-intensity T2-weighted MR image patterns: - 0.037, except for fluid-intensity T2-weighted MR image patterns: + 0.037).

conclusionIn conclusion, older patients with severe low back pain and fluid-intensity T2-weighted MR image patterns were more likely to have lower QOL improvements after OVFs and may therefore need extra support to improve QOL.

Indexed as

Acute DiseaseAgedAged, 80 and overFemaleHumansMaleOsteoporotic FracturesProspective StudiesQuality of LifeRisk FactorsSpinal FracturesEuropean quality of life-5 dimensionsOsteoporotic vertebral fractureQuality of lifeRisk factorVisual analogue scale

Identifiers

PMID32920677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.