Evidence map›Paper›PMID 32920669›Full record

ReviewInflammation research : official journal of the European Histamine Research Society ... [et al.]2020

Cellular and molecular events of inflammation induced transdifferentiation (EMT) and regeneration (MET) in mesenteric mesothelial cells.

Viktória Zsiros, Anna L Kiss

Open access · hybridAbstract readReview
In one paragraph

Review in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Review
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  12. Article
  13. Regulation of Mesothelial Cell Fate during Development and Human Diseases.International journal of molecular sciences · 2022
    Review
  14. Review
  15. Primary and metastatic peritoneal surface malignancies.Nature reviews. Disease primers · 2021
    Review
  16. Inflammation in Focus: The Beginning and the End.Pathology oncology research : POR · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Viktória ZsirosDepartment of Anatomy, Histology and Embryology, Semmelweis University, Tűzoltó u. 58, Budapest, 1094, Hungary.
Anna L KissDepartment of Anatomy, Histology and Embryology, Semmelweis University, Tűzoltó u. 58, Budapest, 1094, Hungary. kiss.anna@med.semmelweis-univ.hu.ORCID http://orcid.org/0000-0001-9191-7102
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review we summarize the cellular and molecular events of inflammation induced epithelial-to-mesenchymal (EMT) and mesothelial-to-macrophage transition (MET) during regeneration. Since the receptor transmits the environmental stimulus, downregulating or upregulating the process on an epigenetic level, the intracellular localization of receptors (signaling organelles: early endosomes or lysosomal degradation: late endosomes) plays a crucial role in the signaling events regulating inflammation and regeneration. Therefore, we focused on the internalization of the receptors as well as the intracellular compartmentalization of signaling molecules during EMT and MET. The review draws the reader's attention to the plasticity of mesothelial cells and supports the idea that during inflammation an ambient macrophage population might derive from mesothelial cells.

Indexed as

Cell TransdifferentiationEpithelial-Mesenchymal TransitionRegenerationAnimalsHumansInflammationMesenteric ArteriesEpithelial-to-mesenchymal transitionInflammationMesenchymal-to-epithelial transitionMesenteric mesothelial cellsRegeneration

Identifiers

PMID32920669
PMCPMC7486969
OpenAlexW3086562298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.