ArticleThe journal of prevention of Alzheimer's disease2020
The Alzheimer's Prevention Registry: A Large Internet-Based Participant Recruitment Registry to Accelerate Referrals to Alzheimer's-Focused Studies.
Article in The journal of prevention of Alzheimer's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02022943 (Alzheimer's Prevention Registry), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Alzheimer's Prevention Registry
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The usage of population and disease registries as pre-screening tools for clinical trials, a systematic review.Systematic reviews · 2024Pooled it
- Representation of Racial and Ethnic Minority Populations in Dementia Prevention Trials: A Systematic Review.The journal of prevention of Alzheimer's disease · 2022Pooled it
- Recruitment and retention in a preclinical AD trial: comparisons between academic and non-academic sites.Alzheimer's research & therapy · 2025Trial
- Evaluating evidence-based recruitment strategies for Alzheimer's disease and related dementias clinical trial research: A literature review.The journal of prevention of Alzheimer's disease · 2026Review
- Enhancing Participation in Alzheimer's Research: A Comparative Study of Community Health Worker -Led and Digital Recruitment Strategies in Hispanic/Latino Communities.Journal of racial and ethnic health disparities · 2026Article
- Brain macrostructure correlates of financial altruism in older adults without dementia.Brain imaging and behavior · 2026Article
- The Alzheimer's Association TrialMatch-Increasing awareness of all dementia trials.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Development of a web platform to advance data-driven recruitment for ADRD research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Effectiveness of a local recruitment registry in older adults in Southern California.BMC medical research methodology · 2025Article
- Enrollment in Alzheimer's disease-focused research registries: altruistic and egocentric motivations.Psychology, health & medicine · 2025Article
- Theory-Based Message Design for Recruitment of Underrepresented Racial/Ethnic Groups Into Alzheimer's-Focused Research Registries.Health education & behavior : the official publication of the Society for Public Health Education · 2025Article
- Lessons from a Pilot Study of a Culturally Tailored Financial Well-Being Intervention Among Latino Family Caregivers.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Synergies, Discrepancies, and Action Priorities: A Statewide Engagement Study to Strengthen Clinical Research in Cerebral Palsy.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Increased reliance on heuristic thinking in mild cognitive impairment.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2025Article
- Neuropsychological profile associated with financial exploitation vulnerability in older adults without dementia.The Clinical neuropsychologist · 2025Article
- Lower entorhinal cortex thickness is associated with greater financial exploitation vulnerability in cognitively unimpaired older adults.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Effectiveness of multimodal participant recruitment in SPARK, a large, online longitudinal research study of autism.Journal of clinical and translational science · 2024Article
- The AlzMatch Pilot Study - Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer's Disease Trials.The journal of prevention of Alzheimer's disease · 2024Article
- Participant completion of longitudinal assessments in an online cognitive aging registry: The role of medical conditions.Alzheimer's & dementia (New York, N. Y.) · 2024Article
- How intention to join an Alzheimer's participant recruitment registry differs by race, ethnicity, sex, and family history: Results from a national survey of US adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundRecruitment for Alzheimer's disease (AD)-focused studies, particularly prevention studies, is challenging due to the public's lack of awareness about study opportunities coupled with studies' inclusion and exclusion criteria, resulting in a high screen fail rate.
objectivesTo develop an internet-based participant recruitment registry for efficiently and effectively raising awareness about AD-focused study opportunities and connecting potentially eligible volunteers to studies in their communities.
methodsIndividuals age 18 and older are eligible to join the Alzheimer's Prevention Registry (APR). Individuals provide first and last name, year of birth, country, and zip/postal code to join the APR; for questions regarding race, ethnicity, sex, family history of AD or other dementia, and diagnosis of cognitive impairment, individuals have the option to select "prefer not to answer." The APR website maintains a list of recruiting studies and contacts members who have opted in by email when new studies are available for enrollment.
resultsAs of December 1, 2019, 346,661 individuals had joined the APR. Members had a mean age of 63.3 (SD 11.7) years and were predominately women (75%). 94% were cognitively unimpaired, 50% reported a family history of AD or other dementia, and of those who provided race, 76% were white. 39% joined the APR as a result of a paid social media advertisement. To date, the APR helped recruit for 82 studies.
conclusionsThe APR is a large, internet-based participant recruitment registry designed to raise awareness about AD prevention research and connect members with enrolling studies in their communities. It has demonstrated the ability to recruit and engage a large number of highly motivated members and assist researchers in meeting their recruitment goals. Future publications will report on the effectiveness of APR for accelerating recruitment and enrollment into AD-focused studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.