Evidence map›Paper›PMID 32918984›Full record

Observational studyResuscitation2020

Trajectories of vital signs in patients with COVID-19.

Marco A F Pimentel, Oliver C Redfern, Robert Hatch, J Duncan Young, Lionel Tarassenko, Peter J Watkinson

Erratum issuedAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Resuscitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Marco A F PimentelInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Oliver C RedfernNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Robert HatchNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address: robert.hatch@doctors.uk.net.
J Duncan YoungNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Lionel TarassenkoInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Peter J WatkinsonNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

Funding

Wellcome Trust WT-103703/Z/14/Z
6 · The paper itself

Abstract

backgroundThe global pandemic of coronavirus disease 2019 (COVID-19) has placed a huge strain on UK hospitals. Early studies suggest that patients can deteriorate quickly after admission to hospital. The aim of this study was to model changes in vital signs for patients hospitalised with COVID-19.

methodsThis was a retrospective observational study of adult patients with COVID-19 admitted to one acute hospital trust in the UK (CV) and a cohort of patients admitted to the same hospital between 2013-2017 with viral pneumonia (VI). The primary outcome was the start of continuous positive airway pressure/non-invasive positive pressure ventilation, ICU admission or death in hospital. We used non-linear mixed-effects models to compare changes in vital sign observations prior to the primary outcome. Using observations and FiO

resultsThere were 497 cases of COVID-19, of whom 373 had been discharged from hospital. 135 (36.2%) of patients experienced the primary outcome, of whom 99 died in hospital. In-hospital mortality was over 4-times higher in the CV than the VI cohort (26.5% vs 6%). For those patients who experienced the primary outcome, CV patients became increasingly hypoxaemic, with a median estimated FiO

conclusionsPatients with COVID-19 who deteriorate in hospital experience rapidly-worsening respiratory failure, with low SpO

Indexed as

BetacoronavirusVital SignsAgedAged, 80 and overCoronavirus InfectionsCOVID-19FemaleHospital MortalityHumansMaleMiddle AgedPandemicsPneumonia, ViralRetrospective StudiesSARS-CoV-2Survival Rate

Identifiers

PMID32918984
PMCPMC7481128

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.