Evidence map›Paper›PMID 32918254›Full record

SynthesisNeuropsychology review2021

Non-Invasive Brain Stimulation Does Not Improve Working Memory in Schizophrenia: A Meta-Analysis of Randomised Controlled Trials.

Nicole P Sloan, Linda K Byrne, Peter G Enticott, Jarrad A G Lum

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neuropsychology review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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  20. European Psychiatric Association guidance on treatment of cognitive impairment in schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicole P SloanCognitive Neuroscience Unit, School of Psychology, Deakin University, Geelong, Victoria, Australia.
Linda K ByrneCognitive Neuroscience Unit, School of Psychology, Deakin University, Geelong, Victoria, Australia.
Peter G EnticottCognitive Neuroscience Unit, School of Psychology, Deakin University, Geelong, Victoria, Australia.
Jarrad A G LumCognitive Neuroscience Unit, School of Psychology, Deakin University, Geelong, Victoria, Australia. jarrad.lum@deakin.edu.au.ORCID 0000-0003-2098-2403
Deakin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poor working memory functioning is commonly found in schizophrenia. A number of studies have now tested whether non-invasive brain stimulation can improve this aspect of cognitive functioning. This report used meta-analysis to synthesise the results of these studies to examine whether transcranial electrical stimulation (tES) or repetitive transcranial magnetic stimulation (rTMS) can improve working memory in schizophrenia. The studies included in this meta-analysis were sham-controlled, randomised controlled trials that utilised either tES or rTMS to treat working memory problems in schizophrenia. A total of 22 studies were included in the review. Nine studies administered rTMS and 13 administered tES. Meta-analysis revealed that compared to sham/placebo stimulation, neither TMS nor tES significantly improved working memory. This was found when working memory was measured with respect to the accuracy on working memory tasks (TMS studies: Hedges' g = 0.112, CI

Indexed as

SchizophreniaTranscranial Direct Current StimulationBrainHumansMemory, Short-TermRandomized Controlled Trials as TopicTranscranial Magnetic StimulationNon-invasive brain stimulationRepetitive Transcranial magnetic stimulation (rTMS)SchizophreniaTranscranial electrical stimulation (tES)Working memory

Identifiers

PMID32918254
OpenAlexW3086896968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.