Evidence map›Paper›PMID 32918186›Full record

ReviewMolecular and cellular biochemistry2021

The emerging roles of circular RNAs in regulating the fate of stem cells.

Ziyao Zhuang, Lingfei Jia, Weiran Li, Yunfei Zheng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ziyao ZhuangDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, People's Republic of China.
Lingfei JiaCentral Laboratory, Peking University School and Hospital of Stomatology, Beijing, 100081, People's Republic of China.
Weiran LiDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, People's Republic of China.
Yunfei ZhengDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, People's Republic of China. yunfei_zheng@bjmu.edu.cn.ORCID http://orcid.org/0000-0003-1899-8051
Peking University · CNKing University · US

Funding

National Natural Science Foundation of China Nos. 81670957National Natural Science Foundation of China Nos. 81700938National Natural Science Foundation of China Nos. 81772876Natural Science Foundation of Beijing Municipality No. 7172239
6 · The paper itself

Abstract

Circular RNAs(circRNAs) are a large family of RNAs shaping covalently closed ring-like molecules and have become a hotspot with thousands of newly published studies. Stem cells are undifferentiated cells and have great potential in medical treatment due to their self-renewal ability and differentiation capacity. Abundant researches have unveiled that circRNAs have unique expression profile during the differentiation of stem cells and could serve as promising biomarkers of these cells. There are key circRNAs relevant to the differentiation, proliferation, and apoptosis of stem cells with certain mechanisms such as sponging miRNAs, interacting with proteins, and interfering mRNA translation. Moreover, several circRNAs have joined in the interplay between stem cells and lymphocytes. Our review will shed lights on the emerging roles of circRNAs in regulating the fate of diverse stem cells.

Indexed as

RNA, CircularAnimalsApoptosisAutoimmune DiseasesBiomarkersCell DifferentiationCell LineageCell Line, TumorCell ProliferationHumansMiceMicroRNAsNeoplasmsNeoplastic Stem CellsPluripotent Stem CellsStem CellsBiomarkersMicroRNAsRNA, CircularApoptosisCell differentiationCell proliferationCircular RNAStem cells

Identifiers

PMID32918186
OpenAlexW3085347749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.