Evidence map›Paper›PMID 32918044›Full record

ArticleLeukemia2021

An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance.

Jacob J Junco, Taylor Chen, Raushan Rashid, Maci Terrell, Vincent U Gant, Matthew Miller, Rachel Rau, H Daniel Lacorazza, Karen R Rabin

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Jacob J JuncoTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA. junco@bcm.edu.ORCID http://orcid.org/0000-0002-2435-7739
Taylor ChenDepartment of Pathology & Immunology, BCM, Houston, TX, USA.
Raushan RashidTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
Maci TerrellTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
Vincent U GantTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.ORCID http://orcid.org/0000-0003-3416-230X
Matthew MillerTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
Rachel RauTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
H Daniel LacorazzaDepartment of Pathology & Immunology, BCM, Houston, TX, USA.
Karen R RabinTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.ORCID http://orcid.org/0000-0002-4081-8195
Baylor College of Medicine · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9M
Molecular epidemiology of acute lymphoblastic leukemia in children with Down syndromeR01CA249867 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LUPO, PHILIP, RABIN, KAREN R · 2020 to 2024
$4.2M
Mechanisms of KLF4 suppression in pediatric leukemiaR01CA207086 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LACORAZZA, DANIEL · 2017 to 2021
$1.8M
DEFINING THE ROLE OF DOT1L IN DNMT3A-MUTANT LEUKEMIAK08CA201611 · NCI · BAYLOR COLLEGE OF MEDICINE · PI RAU, RACHEL E · 2017 to 2019
$486k
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
NCI NIH HHS K08 CA201611NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA207086NCI NIH HHS R01 CA249867NCRR NIH HHS S10 RR024574
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationPenetranceAnimalsFemaleIntegrasesMaleMicePrecursor T-Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene Proteins p21(ras)Transcription FactorsCre recombinaseIntegrasesKRAS protein, humanProto-Oncogene Proteins p21(ras)Transcription Factors

Identifiers

PMID32918044
PMCPMC10204645
OpenAlexW3085965519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.