ArticleNature communications2020
Place cell maps slowly develop via competitive learning and conjunctive coding in the dentate gyrus.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 63 citations in OpenAlex.
- Dynamics of Dentate Gyrus Place Cells and Dentate Spikes during Spatial and Nonspatial Changes in Environments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- The dentate gyrus efficiently converges LEC and MEC inputs into multimodal, highly specific and reliable environmental representations.Nature neuroscience · 2026Article
- Sparsification and decorrelation of granule cell activity in the dentate gyrus by noradrenaline.Communications biology · 2026Article
- Predictive goal coding by dentate gyrus somatostatin-expressing interneurons in male mice.Nature communications · 2025Article
- Agency Modulation of Hippocampal Activity During Spatial Navigation.Research square · 2025Article
- Article
- Synaptic plasticity rules driving representational shifting in the hippocampus.Nature neuroscience · 2025Article
- Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep.bioRxiv : the preprint server for biology · 2025Article
- Experience of Euclidean geometry sculpts the development and dynamics of rodent hippocampal sequential cell assemblies.Nature communications · 2024Article
- Egocentric neural representation of geometric vertex in the retrosplenial cortex.Nature communications · 2024Article
- Differential stability of task variable representations in retrosplenial cortex.Nature communications · 2024Article
- Adult neurogenesis improves spatial information encoding in the mouse hippocampus.Nature communications · 2024Article
- Dominant activities of fear engram cells in the dorsal dentate gyrus underlie fear generalization in mice.PLoS biology · 2024Article
- Stochastic characterization of navigation strategies in an automated variant of the Barnes maze.eLife · 2024Article
- Remapping revisited: how the hippocampus represents different spaces.Nature reviews. Neuroscience · 2024Review
- Spontaneous Dynamics of Hippocampal Place Fields in a Model of Combinatorial Competition among Stable Inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory.The EMBO journal · 2023Review
- Delayed formation of neural representations of space in aged mice.Aging cell · 2023Article
- Assessments of dentate gyrus function: discoveries and debates.Nature reviews. Neuroscience · 2023Review
- Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses.Molecular brain · 2023Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Place cells exhibit spatially selective firing fields that collectively map the continuum of positions in environments; how such activity pattern develops with experience is largely unknown. Here, we record putative granule cells (GCs) and mossy cells (MCs) from the dentate gyrus (DG) over 27 days as mice repetitively run through a sequence of objects fixed onto a treadmill belt. We observe a progressive transformation of GC spatial representations, from a sparse encoding of object locations and spatial patterns to increasingly more single, evenly dispersed place fields, while MCs show little transformation and preferentially encode object locations. A competitive learning model of the DG reproduces GC transformations via the progressive integration of landmark-vector cells and spatial inputs and requires MC-mediated feedforward inhibition to evenly distribute GC representations, suggesting that GCs slowly encode conjunctions of objects and spatial information via competitive learning, while MCs help homogenize GC spatial representations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.