Evidence map›Paper›PMID 32917785›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Type II Cytokines Fine-Tune Thymic T Cell Selection to Offset Murine Central Nervous System Autoimmunity.

Subhasis Barik, Alexis N Cattin-Roy, Tobechukwu K Ukah, Mindy M Miller, Emma Teixeiro, Habib Zaghouani

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Subhasis BarikDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO 65212.ORCID 0000-0002-0488-0434
Alexis N Cattin-RoyDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO 65212.ORCID 0000-0002-4682-6575
Tobechukwu K UkahDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO 65212.ORCID 0000-0002-0815-7040
Mindy M MillerDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO 65212.ORCID 0000-0003-4478-409X
Emma TeixeiroDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO 65212.ORCID 0000-0002-3596-5481
Habib ZaghouaniDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO 65212 zaghouanih@health.missouri.edu.ORCID 0000-0003-4653-0050
University of Missouri · US

Funding

MOLECULAR BASIS OF GENE EXPRESSION AND SIGNAL PROCESSINGT32GM008396 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI HANNINK, MARK · 1991 to 2021
$4.1M
Regulation of Autoimmune EncephalomyelitisR01NS057194 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI ZAGHOUANI, HABIB · 2008 to 2017
$2.9M
TCR signal transduction in the regulation of T cell memoryR01AI110420 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI TEIXEIRO, EMMA · 2015 to 2019
$1.8M
NIAID NIH HHS R01 AI110420NIGMS NIH HHS T32 GM008396NINDS NIH HHS R01 NS057194
6 · The paper itself

Abstract

Early thymic progenitors (ETPs) are bone marrow-derived hematopoietic stem cells that remain multipotent and give rise to a variety of lineage-specific cells. Recently, we discovered a subset of murine ETPs that expresses the IL-4Rα/IL-13Rα1 heteroreceptor (HR) and commits only to the myeloid lineage. This is because IL-4/IL-13 signaling through the HR inhibits their T cell potential and enacts commitment of HR

Indexed as

AnimalsCellular MicroenvironmentDendritic CellsDisease Models, AnimalInterleukin-13Interleukin-4MiceMice, KnockoutMultiple SclerosisThymus GlandT-LymphocytesIl4 protein, mouseInterleukin-13Interleukin-4

Identifiers

PMID32917785
PMCPMC7541690
OpenAlexW3085438870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.