Evidence map›Paper›PMID 32917726›Full record

ArticleThe Journal of biological chemistry2020

Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components.

Chuan-Jin Wu, Xing Li, Connie L Sommers, Kiyoto Kurima, Sunmee Huh, Grace Bugos, Lijin Dong, Wenmei Li, Andrew J Griffith, Lawrence E Samelson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Diverse Functions of the Calcium- and Integrin-Binding Protein Family.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Deficiency inJournal of virology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chuan-Jin WuLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Xing LiMolecular Biology and Genetics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, USA.
Connie L SommersLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Kiyoto KurimaMolecular Biology and Genetics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, USA.
Sunmee HuhLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Grace BugosLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Lijin DongGenetic Engineering Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
Wenmei LiLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Andrew J GriffithMolecular Biology and Genetics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, USA.
Lawrence E SamelsonLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA. Electronic address: samelsonl@helix.nih.gov.
Center for Cancer Research · USNational Cancer Institute · USNational Institute on Deafness and Other Communication Disorders · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

AnimalsCalcium-Binding ProteinsHumansJurkat CellsKeratinocytesMembrane ProteinsMiceMultiprotein ComplexesProteolysisT-LymphocytesUbiquitinationCalcium-Binding ProteinsCIB1 protein, humanCib1 protein, mouseMembrane ProteinsMultiprotein ComplexesTMC6 protein, humanTMC8 protein, humanCIB1epidermodysplasia verruciformisheteromeric complexHPVkeratinocytekeratinocyteslymphocytelymphocytesprotein complexprotein degradationT cellsTMC6TMC8transmembrane channel proteinubiquitin-dependent protease

Identifiers

PMID32917726
PMCPMC7681034
OpenAlexW3086518560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.