Evidence map›Paper›PMID 32917682›Full record

ArticleScience advances2020

B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis.

Qiu-Hui Zeng, Yuan Wei, Xiang-Ming Lao, Dong-Ping Chen, Chun-Xiang Huang, Qian-Yi Lin, Min He, Yuan Liao, Limin Zheng, Bo Li and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

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  14. Metabolites as drivers and targets in rheumatoid arthritis.Clinical and experimental immunology · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Qiu-Hui ZengMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P.R. China.ORCID 0000-0002-8524-6178
Yuan WeiMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P.R. China.ORCID 0000-0001-5694-8835
Xiang-Ming LaoState Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, P.R. China.ORCID 0000-0002-7590-4915
Dong-Ping ChenMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P.R. China.ORCID 0000-0002-3103-5308
Chun-Xiang HuangMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P.R. China.
Qian-Yi LinState Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, P.R. China.
Min HeDepartment of Clinical Laboratory, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, P.R. China.
Yuan LiaoDepartment of Laboratory Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, P.R. China.
Limin ZhengMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P.R. China.
Bo LiDepartment of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, P.R. China.
Guang-Bo ZhangJiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China. kdming@mail.sysu.edu.cn chenyun@njmu.edu.cn zhanggbsuzhou@hotmail.com.ORCID 0000-0002-0965-6503
Yun ChenDepartment of Immunology, Key Laboratory of Immune Microenvironment and Disease, Nanjing Medical University, Nanjing 211166, China. kdming@mail.sysu.edu.cn chenyun@njmu.edu.cn zhanggbsuzhou@hotmail.com.ORCID 0000-0002-4118-362X
Dong-Ming KuangMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P.R. China. kdming@mail.sysu.edu.cn chenyun@njmu.edu.cn zhanggbsuzhou@hotmail.com.ORCID 0000-0003-3570-9717
Sun Yat-sen University · CNGuangzhou University of Chinese Medicine · CNNanjing Medical University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B cells constitute abundant cellular components in inflamed human tissues, but their role in pathogenesis of inflammatory T helper (T

Indexed as

Arthritis, RheumatoidT-Lymphocytes, Helper-InducerGlucoseGlycolysisHumansLymphocyte ActivationGlucose

Identifiers

PMID32917682
PMCPMC11206526
OpenAlexW3083918377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.