Evidence map›Paper›PMID 32917667›Full record

ReviewDevelopment (Cambridge, England)2020

Orchestrating morphogenesis: building the body plan by cell shape changes and movements.

Kia Z Perez-Vale, Mark Peifer

Open access · bronzeAbstract readReview
In one paragraph

Review in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 69 citations in OpenAlex.

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  5. Tissue maps in motion.Nature methods · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kia Z Perez-ValeCurriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Mark PeiferCurriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA peifer@unc.edu.ORCID 0000-0003-1412-3987
University of North Carolina at Chapel Hill · US

Funding

Regulating cell fate and shaping the body plan during morphogenesis and their alteration during oncogenesisR35GM118096 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark A. Peifer · 2016 to 2026
$6.5M
NRSA IN GENETICST32GM007092 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SEKELSKY, JEFF J. · 1985 to 2019
$5.9M
Defining the molecular mechanisms underlying apical-basal polarity establishment and morphogenesisF31GM131521 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEREZ-VALE, KIA ZOLEE · 2019 to 2020
$71k
NIGMS NIH HHS F31 GM131521NIGMS NIH HHS R35 GM118096NIGMS NIH HHS T32 GM007092
6 · The paper itself

Abstract

During embryonic development, a simple ball of cells re-shapes itself into the elaborate body plan of an animal. This requires dramatic cell shape changes and cell movements, powered by the contractile force generated by actin and myosin linked to the plasma membrane at cell-cell and cell-matrix junctions. Here, we review three morphogenetic events common to most animals: apical constriction, convergent extension and collective cell migration. Using the fruit fly

Indexed as

AnimalsBody PatterningCell CommunicationCell MembraneDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianExtracellular MatrixMyosinsDrosophila ProteinsMyosinsCell adhesionCytoskeletonDrosophilaMorphogenesis

Identifiers

PMID32917667
PMCPMC7502592
OpenAlexW3085646700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.