Evidence map›Paper›PMID 32917511›Full record

ReviewTrends in parasitology2020

Maximizing Impact: Can Interventions to Prevent Clinical Malaria Reduce Parasite Transmission?

Robert S McCann, Lauren M Cohee, Jessy Goupeyou-Youmsi, Miriam K Laufer

Open access · greenAbstract readReview
In one paragraph

Review in Trends in parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Biology and epidemiology ofParasite epidemiology and control · 2023
    Review
  6. Observational
  7. Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations.International journal for parasitology. Drugs and drug resistance · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Robert S McCannCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: rmccann@som.umaryland.edu.
Lauren M CoheeCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Jessy Goupeyou-YoumsiMAC Communicable Diseases Action Centre, College of Medicine, University of Malawi, Blantyre, Malawi.
Miriam K LauferCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · USUniversity of Malawi · MW

Funding

The role of monocytes in the pathology of severe malaria.U19AI089683 · NIAID · MICHIGAN STATE UNIVERSITY · PI MATHANGA, DON P · 2010 to 2023
$21.4M
FELLOWSHIP TRAINING PROGRAM IN VACCINOLOGYT32AI007524 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Marcelo B. Sztein · 1997 to 2026
$6.4M
Mentoring in patient-oriented research in global healthK24AI114996 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LAUFER, MIRIAM K. · 2016 to 2025
$1.6M
Interdisciplinary malaria research training in MalawiD43TW010075 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI LAUFER, MIRIAM K., MATHANGA, DON P · 2016 to 2021
$1.1M
Impact of P. falciparum diversity on transmission reducing immunityK23AI135076 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI COHEE, LAUREN M · 2018 to 2022
$940k
FIC NIH HHS D43 TW010075NIAID NIH HHS K23 AI135076NIAID NIH HHS K24 AI114996NIAID NIH HHS T32 AI007524NIAID NIH HHS U19 AI089683
6 · The paper itself

Abstract

Malaria interventions may reduce the burden of clinical malaria disease, the transmission of malaria parasites, or both. As malaria interventions are developed and evaluated, including those interventions primarily targeted at reducing disease, they may also impact parasite transmission. Achieving global malaria eradication will require optimizing the transmission-reducing potential of all available interventions. Herein, we discuss the relationship between malaria parasite transmission and disease, including mechanisms by which disease-targeting interventions might also impact parasite transmission. We then focus on three malaria interventions with strong evidence for reducing the burden of clinical malaria disease and examine their potential for also reducing malaria parasite transmission.

Indexed as

Disease EradicationAnimalsAntimalarialsChemopreventionHumansMalariaMalaria VaccinesPlasmodiumAntimalarialsMalaria VaccinesPlasmodium falciparumRTS,S/AS01 vaccineschool-based preventive treatmentseasonal malaria chemoprevention

Identifiers

PMID32917511
PMCPMC7581555
OpenAlexW3084201383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.