Evidence map›Paper›PMID 32917423›Full record

ReviewOtolaryngologic clinics of North America2020

Transoral Robotic Surgery and De-escalation of Cancer Treatment.

Benjamin Wahle, Jose Zevallos

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Otolaryngologic clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Benjamin WahleDivision of Head and Neck Surgery, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8115, St Louis, MO 63110, USA.
Jose ZevallosDivision of Head and Neck Surgery, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8115, St Louis, MO 63110, USA. Electronic address: jpzevallos@wustl.edu.
Washington University in St. Louis · US

Funding

DEVELOPMENT OF CLINICIAN/RESEARCHERS IN ACADEMIC ENTT32DC000022 · NIDCD · WASHINGTON UNIVERSITY · PI PICCIRILLO, JAY F. · 1989 to 2022
$5.6M
Development of a Four-Class, Molecular Subtyping Diagnostic for HPV-negative Head and Neck CancerR01CA211939 · NCI · WASHINGTON UNIVERSITY · PI HAYES, DAVID N, ZEVALLOS, JOSE P. · 2017 to 2021
$2.3M
NCI NIH HHS R01 CA211939NIDCD NIH HHS T32 DC000022
6 · The paper itself

Abstract

This article outlines the ways that transoral robotic surgery and transoral laser microsurgery relate to treatment de-escalation in the treatment of head and neck cancer. Treatment de-escalation has particular importance in context of human papillomavirus-related oropharynx squamous cell carcinoma, which responds well to therapy but leaves many survivors with decades of treatment-related sequelae. We compare these less invasive transoral approaches with previously used open approaches to the oropharynx. We discuss the topic of treatment de-escalation in human papillomavirus-related disease and outline completed and ongoing clinical trials investigating the choice of primary treatment modality and de-escalation of adjuvant therapy.

Indexed as

Robotic Surgical ProceduresCarcinoma, Squamous CellHumansLaser TherapyMicrosurgeryOropharyngeal NeoplasmsPapillomaviridaeHuman papillomavirus–associated oropharynx cancerSquamous cell carcinoma of the oropharynxTransoral laser microsurgeryTransoral robotic surgeryTreatment de-escalationTreatment deintensification

Identifiers

PMID32917423
PMCPMC8060871
OpenAlexW3084062047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.