Evidence map›Paper›PMID 32917356›Full record

ArticleRespiratory medicine2020

Significant reduction in hospital admissions for acute exacerbation of chronic obstructive pulmonary disease in Hong Kong during coronavirus disease 2019 pandemic.

King Pui Florence Chan, Ting Fung Ma, Wang Chun Kwok, Jackson Ka Chun Leung, Ka Yan Chiang, James Chung Man Ho, David Chi Leung Lam, Terence Chi Chun Tam, Mary Sau Man Ip, Pak Leung Ho

Open access · bronzeAbstract read
In one paragraph

Article in Respiratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
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  12. COPD Exacerbations, Air Pollutant Fluctuations, and Individual-Level Factors in the Pandemic Era.International journal of chronic obstructive pulmonary disease · 2025
    Article
  13. Long-Term Effects of COVID-19 on Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. COPD Exacerbations Before and During COVID-19 in France, Germany, Italy, the UK and the US.International journal of chronic obstructive pulmonary disease · 2024
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

King Pui Florence ChanDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China. Electronic address: ckp663@ha.org.hk.
Ting Fung MaDepartment of Statistics, University of Wisconsin-Madison, USA.
Wang Chun KwokDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Jackson Ka Chun LeungDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Ka Yan ChiangDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
James Chung Man HoDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
David Chi Leung LamDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Terence Chi Chun TamDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Mary Sau Man IpDepartment of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Pak Leung HoDepartment of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
Queen Mary Hospital · CNUniversity of Hong Kong · HKUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic respiratory diseases are risk factors for severe disease in coronavirus disease 2019 (COVID-19). Respiratory tract infection is one of the commonest causes of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). There has not been evidence suggesting the link between COVID-19 and AECOPD, especially in places with dramatic responses in infection control with universal masking and aggressive social distancing.

methodsThis is a retrospective study to assess the number of admissions of AECOPD in the first three months of 2020 in Queen Mary Hospital with reference to the admissions in past five years. Log-linear model was used for statistical inference of covariates, including percentage of masking, air quality health index and air temperature.

resultsThe number of admissions for AECOPD significantly decreased by 44.0% (95% CI 36.4%-52.8%, p < 0.001) in the first three months of 2020 compared with the monthly average admission in 2015-2019. Compare to same period of previous years, AECOPD decreased by 1.0% with each percent of increased masking (p < 0.001) and decreased by 3.0% with increase in 1 °C in temperature (p = 0.045). The numbers of admissions for control diagnoses (heart failure, intestinal obstruction and iron deficiency anaemia) in the same period in 2020 were not reduced.

conclusionsThe number of admissions for AECOPD decreased in first three months of 2020, compared with previous years. This was observed with increased masking percentage and social distancing in Hong Kong. We postulated universal masking and social distancing during COVID-19 pandemics both contributed in preventing respiratory tract infections hence AECOPD.

Indexed as

Coronavirus InfectionsCOVID-19PandemicsPneumonia, ViralPulmonary Disease, Chronic ObstructiveRespiratory Tract InfectionsAir PollutionBetacoronavirusFemaleHong KongHumansMaleMiddle AgedPatient AdmissionRespiratory Protective DevicesRetrospective StudiesChronic obstructive pulmonary diseaseCoronavirus disease 2019Hospitalization

Identifiers

PMID32917356
PMCPMC7354382
OpenAlexW3042562669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.