ArticleBMC complementary medicine and therapies2020
The effect of Malus doumeri leaf flavonoids on oxidative stress injury induced by hydrogen peroxide (H
Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Nephroprotective and therapeutic potential of3 Biotech · 2025Article
- An Interpretable Screening Approach Derived Through XGBoost Regression for the Discovery of Hypolipidemic Contributors in Chinese Hawthorn Leaf and its Counterfeit Malus Doumeri Leaf.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- Planting conditions can enhance the bioactivity of mulberry by affecting its composition.Frontiers in plant science · 2023Article
- Feasibility study on the use of "Qi-tonifying medicine compound" as an anti-fatigue functional food ingredient based on network pharmacology and molecular docking.Frontiers in nutrition · 2023Article
- Autophagy-induced mesenchymal stem cell-derived extracellular vesicles ameliorated renal fibrosis in anBioImpacts : BI · 2023Article
- Comparison of the Antihypertensive Activity of Phenolic Acids.Molecules (Basel, Switzerland) · 2022Article
- Photoprotection Differences between Dominant Tree Species at Mid- and Late-Successional Stages in Subtropical Forests in Different Seasonal Environments.International journal of molecular sciences · 2022Article
- Intervening Effects and Molecular Mechanism of Quercitrin on PCV2-Induced Histone Acetylation, Oxidative Stress and Inflammatory Response in 3D4/2 Cells.Antioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIn this study, Malus doumeri leaf flavonoids (MDLF) were used as the research object to observe their in vitro antioxidant stress ability. Hydrogen peroxide (H
methodsMTT, flow cytometry, and qPCR were used to verify the effect of MDLF.
resultsIn vitro cell experiments showed that at a concentration of 0-160 μg/mL, MDLF did not affect the normal proliferation of human embryonic kidney 293 T cells (HEK 293 T cells), and MDLF had no cytotoxic effect in this concentration range. It was found that MDLF could maintain the survival of HEK 293 T cells (82.6%) at a high concentration (160 μg/mL). Morphological observation also found that MDLF can inhibit the cell structure imperfection caused by H
conclusionFrom the experimental results, it was observed that MDLF has a strong anti-oxidation ability in vitro, and it can interfere with the oxidative stress damage caused by H
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Registered trials
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