ArticleBMC oral health2020
The change of teeth color, whiteness variations and its psychosocial and self-perception effects when using low vs. high concentration bleaching gels: a one-year follow-up.
Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03217994 (Efficacy of a 6% Hydrogen Peroxide Tooth Bleaching Agent Without Ligth), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of a 6% Hydrogen Peroxide Tooth Bleaching Agent Without Ligth
Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- One-Year Color Stability of a Reduced 37.5% Hydrogen Peroxide In-Office Bleaching Protocol: A Randomized Clinical Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Trial
- Effect of copaiba oil-resin on dental sensitivity control and color change after bleaching: A randomized clinical trial.Clinical oral investigations · 2025Trial
- Clinical evaluation of in-office bleaching with low, medium, and high concentrate hydrogen peroxide: a 6-month a double-blinded randomized controlled trial.Clinical oral investigations · 2025Trial
- Clinical performance of 6% hydrogen peroxide containing TiOLasers in medical science · 2022Trial
- Colorimetric evaluation after in-office tooth bleaching with violet LED: 6- and 12-month follow-ups of a randomized clinical trial.Clinical oral investigations · 2022Trial
- Validation of the brazilian version of the oral health impact profile - Aesthetic questionnaire.Brazilian dental journalTrial
- Evaluation of tooth sensitivity and whitening effects of tooth whitening agents containing calcium, hydroxyapatite and fluoride.Odontology · 2026Article
- Article
- Multidisciplinary approach for endodontic microsurgery combined with crown lengthening of tooth defects with apical lesion: a case series.BMC oral health · 2026Article
- Clinical myths in dental bleaching: an evidence-based structured narrative review.Brazilian oral research · 2026Review
- In Vitro Comparison of Three Chairside Bleaching Protocols: Effects on Enamel Microhardness, Colour, and Qualitative Cytotoxicity Risk.Dentistry journal · 2025Article
- Comparative evaluation to composite resin bleaching using ozone-enhanced low-concentration hydrogen peroxide.Scientific reports · 2025Article
- Hydrogen Peroxide-Free Color Correctors for Tooth Whitening in Adolescents and Young Adults: A Systematic Review of In Vitro and Clinical Evidence.Dentistry journal · 2025Review
- Evaluation of the Effectiveness of Different Types of Professional Tooth Whitening: A Systematic Review.Bioengineering (Basel, Switzerland) · 2024Review
- Probiotics for oral health: a critical evaluation of bacterial strains.Frontiers in microbiology · 2024Review
- Assessment of Color Change, Esthetic Perception, Treatment Satisfaction, and Side Effects Following the Use of Over-the-Counter Whitening Products.Acta stomatologica Croatica · 2023Article
- Repeatability of dental shade by digital spectrophotometry in current, former, and never smokers.Odontology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundDental bleaching in traditional concentrations generates greater sensitivity. In this respect, new systems of lower concentration of hydrogen peroxide for tooth bleaching appeared, with color stability unknown over time. The aim of this study was to compare the change and stability of color with low-concentration (6%) hydrogen peroxide gel in an in-office bleaching setting relative to conventional 37.5% gel, including their effects on psychosocial and esthetic self-perception, after 1 year.
methodsPatients (n = 25) were assessed at 12 months post bleaching treatment (whitening with 6% chemo-activated alkaline formula gel versus 37.5% traditional concentration gel). Color changes were measured objectively using total variation in color (ΔE), and subjectively using Vita Classical and Vita Bleached scale (ΔSGU) by calibrated evaluators (Kappa = 0.85). The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) and Oral Health Impact Profile (OHIP-14) aesthetic questionnaires were used to measure the self-perception and the psychosocial impact of the bleaching protocols.
resultsThe effect (ΔE) of 37.5% HP (8.37 ± 2.73) was significantly better than that of 6% HP (5.27 ± 2.53) in terms of color rebound after 1 year of follow-up. There were significant differences in psychosocial impact and esthetic self-perception measurements prior to bleaching versus one-year post-whitening time points; positive effects were maintained.
conclusionsLow concentration (6%) achieved effective bleaching with good stability after 1 year, accompanied by a positive psychosocial impact and enhanced self-perception at follow-up.
trial registrationNCT03217994 (before enrollment of the first participant). Data register: July 14, 2017.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.