ArticleBMC geriatrics2020
Multimorbidity, physical frailty, and self-rated health in older patients with atrial fibrillation.
Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Prevalence, Incidence, and Impact of Cancer in Atrial Fibrillation: A Systematic Review and Meta-Analysis of 70,000,000 Patients.Health science reports · 2026Review
- Characterising Multimorbidity in Adults With Heart Failure: A Latent Class Analysis.Heart, lung & circulation · 2026Article
- The clinical frailty scale score in older persons (≥ 65 years) admitted via the emergency department: a prospective cohort study.BMC geriatrics · 2026Article
- Frailty and transitions across cardiometabolic disease states: evidence from multistate models in a 16-year Chinese cohort.npj aging · 2025Article
- Need for Engagement in Stroke Prevention Shared Decision-Making in Older Adults with Atrial Fibrillation and Multimorbidity.Advances in geriatric medicine and research · 2025Article
- Hospital healthcare utilisation in patients with atrial fibrillation: the role of multimorbidity and age.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
- Article
- Frailty prevalence in older adults with atrial fibrillation: A cross-sectional study in a resource-limited setting.PloS one · 2024Article
- Cardiovascular and renal multimorbidity increase risk of atrial fibrillation in the PREVEND cohort.Open heart · 2023Article
- Investigating the relationship between self-perception of fracture risk and prior fracture: findings from the Hertfordshire Cohort Study.Aging clinical and experimental research · 2023Article
- Impact of Multimorbidity and Polypharmacy on Clinical Outcomes of Elderly Chinese Patients with Atrial Fibrillation.Journal of clinical medicine · 2022Article
- Association of social determinants of health with frailty, cognitive impairment, and self-rated health among older adults.PloS one · 2022Article
- Cardiometabolic diseases, frailty, and healthcare utilization and expenditure in community-dwelling Chinese older adults.Scientific reports · 2021Article
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Authors and funding
11 authors.
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Abstract
backgroundHolistic care models emphasize management of comorbid conditions to improve patient-reported outcomes in treatment of atrial fibrillation (AF). We investigated relations between multimorbidity, physical frailty, and self-rated health (SRH) among older adults with AF.
methodsPatients (n = 1235) with AF aged 65 years and older were recruited from five medical centers in Massachusetts and Georgia between 2015 and 2018. Ten previously diagnosed cardiometabolic and 8 non-cardiometabolic conditions were assessed from medical records. Physical Frailty was assessed with the Cardiovascular Health Study frailty scale. SRH was categorized as either "excellent/very good", "good", and "fair/poor". Separate multivariable ordinal logistic models were used to examine the associations between multimorbidity and SRH, physical frailty and SRH, and multimorbidity and physical frailty.
resultsOverall, 16% of participants rated their health as fair/poor and 14% were frail. Hypertension (90%), dyslipidemia (80%), and heart failure (37%) were the most prevalent cardiometabolic conditions. Arthritis (51%), anemia (31%), and cancer (30%), the most common non-cardiometabolic diseases. After multivariable adjustment, patients with higher multimorbidity were more likely to report poorer health status (Odds Ratio (OR): 2.15 [95% CI: 1.53-3.03], ≥ 8 vs 1-4; OR: 1.37 [95% CI: 1.02-1.83], 5-7 vs 1-4), as did those with more prevalent cardiometabolic and non-cardiometabolic conditions. Patients who were pre-frail (OR: 1.73 [95% CI: 1.30-2.30]) or frail (OR: 6.81 [95% CI: 4.34-10.68]) reported poorer health status. Higher multimorbidity was associated with worse frailty status.
conclusionsMultimorbidity and physical frailty were common and related to SRH. Our findings suggest that holistic management approaches may influence SRH among older patients with AF.
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