ArticleBMC genomics2020
Developmentally regulated activation of defense allows for rapid inhibition of infection in age-related resistance to Phytophthora capsici in cucumber fruit.
Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- 1,2,4-Triazolium compounds as anti-oomycete leads against Phytophthora capsici.Pest management science · 2026Article
- When Metabolomics Meets Quantitative Genetics: An Integrative Strategy to Elucidate Plant Resistance Mechanisms.Plant, cell & environment · 2026Review
- Integrating Single-Cell and Spatial Multi-Omics to Decode Plant-Microbe Interactions at Cellular Resolution.Microorganisms · 2026Review
- Rootstock Selection for Resisting CucumberPlants (Basel, Switzerland) · 2025Article
- Genome-Wide Association Study of Cuticle and Lipid Droplet Properties of Cucumber (International journal of molecular sciences · 2024Article
- A multifaceted crosstalk between brassinosteroid and gibberellin regulates the resistance of cucumber to Phytophthora melonis.The Plant journal : for cell and molecular biology · 2024Article
- Genetic factors acting prior to dormancy in sour cherry influence bloom time the following spring.Journal of experimental botany · 2024Article
- Genetic diversity, mating type and pathogenicity of two3 Biotech · 2024Article
- Shoot Maturation Strengthens FLS2-Mediated Resistance toMolecular plant-microbe interactions : MPMI · 2023Article
- Distinct function of SPL genes in age-related resistance in Arabidopsis.PLoS pathogens · 2023Article
- Identification of QTL associated with resistance to Phytophthora fruit rot in cucumber (Frontiers in plant science · 2023Article
- Pathogen-triggered changes in plant development: Virulence strategies or host defense mechanism?Frontiers in microbiology · 2023Review
- Differences in the Proteomic and Metabolomic Response ofFrontiers in microbiology · 2022Article
- Enhanced Age-Related Resistance to Tomato Yellow Leaf Curl Virus in Tomato Is Associated With Higher Basal Resistance.Frontiers in plant science · 2021Article
- Quantitative High-Throughput, Real-Time Bioassay for Plant Pathogen GrowthFrontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundAge-related resistance (ARR) is a developmentally regulated phenomenon conferring resistance to pathogens or pests. Although ARR has been observed in several host-pathogen systems, the underlying mechanisms are largely uncharacterized. In cucumber, rapidly growing fruit are highly susceptible to Phytophthora capsici but become resistant as they complete exponential growth. We previously demonstrated that ARR is associated with the fruit peel and identified gene expression and metabolomic changes potentially functioning as preformed defenses.
resultsHere, we compare the response to infection in fruit at resistant and susceptible ages using microscopy, quantitative bioassays, and weighted gene co-expression analyses. We observed strong transcriptional changes unique to resistant aged fruit 2-4 h post inoculation (hpi). Microscopy and bioassays confirmed this early response, with evidence of pathogen death and infection failure as early as 4 hpi and cessation of pathogen growth by 8-10 hpi. Expression analyses identified candidate genes involved in conferring the rapid response including those encoding transcription factors, hormone signaling pathways, and defenses such as reactive oxygen species metabolism and phenylpropanoid biosynthesis.
conclusionThe early pathogen death and rapid defense response in resistant-aged fruit provide insight into potential mechanisms for ARR, implicating both pre-formed biochemical defenses and developmentally regulated capacity for pathogen recognition as key factors shaping age-related resistance.
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