Evidence map›Paper›PMID 32917125›Full record

SynthesisNeurorehabilitation and neural repair2020

Physiotherapy in Parkinson's Disease: A Meta-Analysis of Present Treatment Modalities.

Danique L M Radder, Ana Lígia Silva de Lima, Josefa Domingos, Samyra H J Keus, Marlies van Nimwegen, Bastiaan R Bloem, Nienke M de Vries

4 registry-linked trialsOpen access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neurorehabilitation and neural repair, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 157 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 22 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05710588 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effectiveness of Motor-motor and Motor-cognitive Dual-task Training Interventions on Balance in People With Parkinson's Disease: a Feasibility Study of a Randomized Clinical Trial

TypeinterventionalSponsorUniversity of PlymouthRan2022 to 2023Enrolled10ConditionsParkinson's DiseaseArmsmotor-motor dual-task training, motor-cognitive dual-task training
NCT07068217 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Metronome-Based Structured Rhythmic Exercise Program on Freezing and Gait Parameters in Parkinson Disease

TypeinterventionalSponsorMedipol UniversityRan2025 to 2026Enrolled26ConditionsPARKINSON DISEASE (Disorder)ArmsExercise
NCT07659288 nacompletednot on this mapstarted 2025, after this paper: background citation

Differential Motor and Cognitive Responses to Two Virtual Reality-Based Rehabilitation Approaches in Parkinson's Disease: A Pilot Comparative Study

TypeinterventionalSponsorNeuro Group XR Inc.Ran2025 to 2025Enrolled16ConditionsParkinson s DiseaseArmsImmersive Virtual Reality, Non-Immersive Virtual Reality
NCT07705620 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Behavioral Digital Intervention For Parkinson's Disease: Protocol For A Quasi-Experimental Study Examining Feasibility, Physical Activity, And Exploratory Patient-Reported Outcomes

TypeinterventionalSponsorEgas Moniz - Cooperativa de Ensino Superior, CRLRan2026 to 2027Enrolled68ConditionsParkinson Disease, Exercise TrainingArmsDigital Exercise Program
3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 22 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Danique L M RadderRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.ORCID 0000-0001-7363-6681
Ana Lígia Silva de LimaRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.
Josefa DomingosRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.
Samyra H J KeusRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.
Marlies van NimwegenRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.
Bastiaan R BloemRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.
Nienke M de VriesRadboud University Medical Center, Nijmegen, Gelderland, The Netherlands.
Radboud University Nijmegen · NLUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysiotherapy is a commonly prescribed intervention for people with Parkinson's disease (PD). Conventional types of physiotherapy have been studied extensively, while novel modalities are being developed and evaluated.

objectiveTo evaluate the effectiveness of conventional and more recent physiotherapy interventions for people with PD. The meta-analysis performed as part of the 2014

methodsWe performed a systematic search in PubMed, CINAHL, Embase, and Web of Science. Randomized controlled trials comparing any physiotherapy intervention with no intervention or sham treatment were included. Trials were classified into 12 categories: conventional physiotherapy, resistance training, treadmill training, strategy training, dance, martial arts, aerobic exercises, hydrotherapy, balance and gait training, dual tasking, exergaming, and Nordic walking. Outcomes included motor symptoms, balance, gait, and quality of life, and are presented as standardized mean differences. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach was used to systematically appraise methodological quality.

resultsA total of 191 trials with 7998 participants were included. Conventional physiotherapy significantly improved motor symptoms, gait, and quality of life. Resistance training improved gait. Treadmill training improved gait. Strategy training improved balance and gait. Dance, Nordic walking, balance and gait training, and martial arts improved motor symptoms, balance, and gait. Exergaming improved balance and quality of life. Hydrotherapy improved balance. Finally, dual task training did not significantly improve any of the outcomes studied.

conclusionsThis meta-analysis provides a comprehensive overview of the evidence for the effectiveness of different physiotherapy interventions in the management of PD, allowing clinicians and patients to make an evidence-based decision for specific treatment modalities. Further work is needed to directly compare the relative efficacy of the various treatments.

Indexed as

Neurological RehabilitationOutcome Assessment, Health CarePhysical Therapy ModalitiesHumansParkinson DiseaseEuropean Physiotherapy Guidelineguidelinemeta-analysisParkinson’s diseasephysiotherapyreview

Identifiers

PMID32917125
PMCPMC7564288
OpenAlexW3086490816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.