Evidence map›Paper›PMID 32916962›Full record

ArticleInternational journal of molecular sciences2020

Evaluation of Radioiodinated Fluoronicotinamide/Fluoropicolinamide-Benzamide Derivatives as Theranostic Agents for Melanoma.

Chao-Cheng Chen, Yang-Yi Chen, Yi-Hsuan Lo, Ming-Hsien Lin, Chih-Hsien Chang, Chuan-Lin Chen, Hsin-Ell Wang, Chun-Yi Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Targeting Melanin in Melanoma with Radionuclide Therapy.International journal of molecular sciences · 2022
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chao-Cheng ChenDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.
Yang-Yi ChenDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.
Yi-Hsuan LoDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.
Ming-Hsien LinDepartment of Nuclear Medicine, Taipei City Hospital Zhongxiao Branch, Taipei 115, Taiwan.
Chih-Hsien ChangDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.
Chuan-Lin ChenDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.
Hsin-Ell WangDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.
Chun-Yi WuDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.ORCID 0000-0002-8217-1692
National Yang Ming Chiao Tung University · TWCheng Hsin General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant melanoma is the most harmful type of skin cancer and its incidence has increased in this past decade. Early diagnosis and treatment are urgently desired. In this study, we conjugated picolinamide/nicotinamide with the pharmacophore of

Indexed as

AnimalsBenzamidesCell Line, TumorHumansIodine RadioisotopesMelaninsMelanoma, ExperimentalMice, Inbred C57BLNiacinamidePicolinic AcidsPrecision MedicineRadionuclide ImagingRadiopharmaceuticalsSkin NeoplasmsXenograft Model Antitumor AssaysBenzamidesIodine-131Iodine RadioisotopesMelaninsN-(2-diethylaminoethyl)-4-(4-fluorobenzamido)-5-iodo-2-methoxybenzamideNiacinamidepicolinamidePicolinic AcidsRadiopharmaceuticals131I-iodofluoronicotiamide benzamide (131I-IFNABZA)131I-iodofluoropicolinamide benzamide (131I-IFPABZA)melanomatheranostic agent

Identifiers

PMID32916962
PMCPMC7554940
OpenAlexW3084228770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.