Evidence map›Paper›PMID 32916960›Full record

ArticleInternational journal of molecular sciences2020

STIM1 Deficiency Leads to Specific Down-Regulation of ITPR3 in SH-SY5Y Cells.

Carlos Pascual-Caro, Yolanda Orantos-Aguilera, Irene Sanchez-Lopez, Jaime de Juan-Sanz, Jan B Parys, Estela Area-Gomez, Eulalia Pozo-Guisado, Francisco Javier Martin-Romero

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Impact of static magnetic field exposure onJournal of advanced veterinary and animal research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Target Molecules of STIM Proteins in the Central Nervous System.Frontiers in molecular neuroscience · 2020
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Carlos Pascual-CaroDepartment of Biochemistry and Molecular Biology, School of Life Sciences and Institute of Molecular Pathology and Biomarkers, University of Extremadura, 06006 Badajoz, Spain.
Yolanda Orantos-AguileraDepartment of Biochemistry and Molecular Biology, School of Life Sciences and Institute of Molecular Pathology and Biomarkers, University of Extremadura, 06006 Badajoz, Spain.
Irene Sanchez-LopezDepartment of Biochemistry and Molecular Biology, School of Life Sciences and Institute of Molecular Pathology and Biomarkers, University of Extremadura, 06006 Badajoz, Spain.
Jaime de Juan-SanzSorbonne Universités and Institut du Cerveau et de la Moelle Epinière (ICM) - Hôpital Pitié-Salpêtrière, Inserm, CNRS, 75013 Paris, France.ORCID 0000-0002-1212-5623
Jan B ParysDepartment of Cellular and Molecular Medicine, Leuven Kanker Instituut, KU Leuven, B-3000 Leuven, Belgium.ORCID 0000-0002-3591-4967
Estela Area-GomezDepartment of Neurology, Columbia University Medical Center, New York, NY 10032-3748, USA.
Eulalia Pozo-GuisadoDepartment of Cell Biology, School of Medicine and Institute of Molecular Pathology and Biomarkers, University of Extremadura, 06006 Badajoz, Spain.
Francisco Javier Martin-RomeroDepartment of Biochemistry and Molecular Biology, School of Life Sciences and Institute of Molecular Pathology and Biomarkers, University of Extremadura, 06006 Badajoz, Spain.ORCID 0000-0001-6796-7396
Universidad de Extremadura · ESCentre National de la Recherche Scientifique · FRColumbia University Irving Medical Center · USKU Leuven · BE

Funding

Role of C99 in the regulation of lipid metabolism- Relevance to Alzheimer's diseaseR01AG056387 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AREA GOMEZ, ESTELA · 2017 to 2021
$2.1M
Junta de Extremadura GR18084Junta de Extremadura IB16088Ministerio de Ciencia, Innovación y Universidades BFU2017-82716-PNIA NIH HHS R01 AG056387
6 · The paper itself

Abstract

STIM1 is an endoplasmic reticulum (ER) protein that modulates the activity of a number of Ca

Indexed as

Calcium SignalingCell Line, TumorDown-RegulationGene Knockout TechniquesHumansInositol 1,4,5-Trisphosphate ReceptorsMitochondriaNeoplasm ProteinsStromal Interaction Molecule 1Inositol 1,4,5-Trisphosphate ReceptorsITPR3 protein, humanNeoplasm ProteinsSTIM1 protein, humanStromal Interaction Molecule 1calciumendoplasmic reticulumIP3 receptormitochondrianeurodegenerationSTIM1

Identifiers

PMID32916960
PMCPMC7555297
OpenAlexW3084154454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.