Evidence map›Paper›PMID 32916866›Full record

ReviewBrain sciences2020

The Anatomical and Functional Heterogeneity of the Mediodorsal Thalamus.

Ioana Antoaneta Georgescu, Daniela Popa, Leon Zagrean

Open access · goldAbstract readReview
In one paragraph

Review in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Associations among mediodorsal thalamic-ventrolateral prefrontal cortical white matter fiber dispersion and OCD-related incompleteness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Distinct Brain Drivers and Shared Cerebello-Cortical Input in ADCY5 and SGCE Hyperkinetic Movements.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  6. Article
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  14. Ultra-high Field fMRI Reveals Effect of Ketamine on Vocal Processing in Common Marmosets.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  15. Article
  16. GPe Projections to the Retrorubral Field Give Rise to Diverging GABAergic and DAergic Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ioana Antoaneta GeorgescuDivision of Physiology and Neuroscience, Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, nr 8, Sector 5, 050474 Bucharest, Romania.
Daniela PopaDivision of Physiology and Neuroscience, Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, nr 8, Sector 5, 050474 Bucharest, Romania.
Leon ZagreanDivision of Physiology and Neuroscience, Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, nr 8, Sector 5, 050474 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROCentre National de la Recherche Scientifique · FR

Funding

Carol Davila University of Medicine and Pharmacy, Bucharest, Romania Project number 819/11.01.2019
6 · The paper itself

Abstract

The mediodorsal nucleus (MD) represents just one piece of a complex relay structure situated within the brain, called the thalamus. MD is characterized by its robust interconnections with other brain areas, especially with limbic-related structures. Given the close anatomo-functional relationship between the MD and the limbic system, this particular thalamic nucleus can directly influence various affective behaviors and participate in cognition. In this work, we review data collected from multiple anatomical studies conducted in rodent, human, and non-human primates, highlighting the complexity of this structure and of the neural networks in which it takes part. We provide proof that the MD is involved in the unification of several anatomical structures, being able to process the information and influence the activity in numerous cortical and subcortical neural circuits. Moreover, we uncover intrinsic and extrinsic mechanisms that offer MD the possibility to execute and control specific high functions of the nervous system. The collected data indicate the great importance of the MD in the limbic system and offer relevant insight into the organization of thalamic circuits that support MD functions.

Indexed as

anatomybehaviorcognitionemotionlimbic systemmediodorsal thalamusprefrontal cortex

Identifiers

PMID32916866
PMCPMC7563683
OpenAlexW3083793681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.