Evidence map›Paper›PMID 32916801›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Self-Collected versus Healthcare Worker-Collected Swabs in the Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2.

Johan H Therchilsen, Christian von Buchwald, Anders Koch, Susanne Dam Nielsen, Daniel B Rasmussen, Rebekka Faber Thudium, Nikolai S Kirkby, Daniel E T Raaschou-Pedersen, Johan S Bundgaard, Kasper Iversen and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05209178 (Diagnostic Accuracy of Self-collected Versus Healthcare Collected Anterior Nose Swabs for SARS-CoV-2 Detection - a Randomized Controlled Trial.), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05209178 nacompletednot on this mapstarted 2022, after this paper: background citation

Diagnostic Accuracy of Self-collected Versus Healthcare Collected Anterior Nose Swabs for SARS-CoV-2 Detection - a Randomized Controlled Trial.

TypeinterventionalSponsorRigshospitalet, DenmarkRan2022 to 2022Enrolled3,070ConditionsCOVID-19 PandemicArmsCollection of nasal and oropharyngeal specimen for COVID19 antigen test
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Self-swabbing versus assisted swabbing for viral detection by qRT-PCR: the experience from SARS-CoV-2 based on a meta-analysis of six prospectively designed evaluations conducted in a UK setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Pooled it
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  16. Danish citizens' preferences for at-home oropharyngeal/nasal SARS-CoV-2 specimen collection.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Johan H TherchilsenDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Christian von BuchwaldDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Anders KochDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Susanne Dam NielsenDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Daniel B RasmussenDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Rebekka Faber ThudiumDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Nikolai S KirkbyDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Daniel E T Raaschou-PedersenDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Johan S BundgaardDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Kasper IversenDepartment of Cardiology, Copenhagen University Hospital Herlev, 2730 Herlev, Denmark.
Henning BundgaardDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Tobias TodsenDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.ORCID 0000-0003-3267-3560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to compare the sensitivity of self-collected versus healthcare worker (HCW)-collected swabs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) testing. Symptomatic individuals referred for SARS-CoV-2 testing were invited to provide mobile-phone video-instructed self-collected oropharyngeal and nasal samples followed by a HCW-collected oropharyngeal sample. All samples were sent for analysis to the same microbiology laboratory, and the number of SARS-CoV-2-positive participants in the two tests was compared. A total of 109 participants were included, and 19 participants had SARS-CoV-2-positive results. The diagnostic sensitivity of the self-collected and HCW-collected swabs was 84.2% and 89.5%, respectively, with an acceptable agreement, Cohens kappa 0.82,

Indexed as

COVID-19COVID-19 diagnostic testingsevere acute respiratory syndrome coronavirus 2

Identifiers

PMID32916801
PMCPMC7554687

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.