ReviewInternational journal of molecular sciences2020
Molecular Mechanisms of Reconsolidation-Dependent Memory Updating.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Aging disrupts transcriptional programs for memory updating in the dorsal hippocampus and reveals a required role forbioRxiv : the preprint server for biology · 2026Article
- Judicial assessment of testimonial reliability after EMDR therapy: a case-series analysis.Frontiers in psychology · 2026Article
- Theta-encoded information flow from dorsal CA1 to prelimbic cortex drives memory reconsolidation.iScience · 2025Article
- How Fear Memory is Updated: From Reconsolidation to Extinction?Neuroscience bulletin · 2025Review
- Memory Reconsolidation Updating in Substance Addiction: Applications, Mechanisms, and Future Prospects for Clinical Therapeutics.Neuroscience bulletin · 2025Review
- Memory reconsolidation impairment by amyloid beta (1-42) and its prevention by non-competitive antagonists of NMDA receptors.Frontiers in cellular neuroscience · 2025Article
- Memory reconsolidation: a proposed change mechanism for the arts therapies.Frontiers in cognition · 2025Article
- Neuromodulatory transcranial magnetic stimulation (TMS) changes functional connectivity proportional to the electric-field induced by the TMS pulse.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Termination of convulsion seizures by destabilizing and perturbing seizure memory engrams.Science advances · 2024Article
- Advances in fear memory erasure and its neural mechanisms.Frontiers in neurology · 2024Review
- Non-competitive NMDA antagonist MK-801 prevents memory reconsolidation impairment caused by protein synthesis inhibitors in young chicks.Frontiers in pharmacology · 2024Article
- Restoring GABAFrontiers in molecular neuroscience · 2024Article
- Reduced Expression of the Htr2a, Grin1, and Bdnf Genes and Cognitive Inflexibility in a Model of High Compulsive Rats.Molecular neurobiology · 2023Article
- Continuous Theta-Burst Stimulation to the Right Dorsolateral Prefrontal Cortex May Increase Potentiated Startle in Healthy Individuals.Biological psychiatry global open science · 2023Article
- Enhancing Psychological Interventions for Post-Traumatic Stress Disorder (PTSD) Treatment with Memory Influencing Drugs.Current neuropharmacology · 2023Review
- Cognitive neuroscience perspective on memory: overview and summary.Frontiers in human neuroscience · 2023Article
- Spatial contextual recognition memory updating is modulated by dopamine release in the dorsal hippocampus from the locus coeruleus.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- EphrinA4 mimetic peptide impairs fear conditioning memory reconsolidation in lateral amygdala.Scientific reports · 2022Article
- On the effect of hippocampal c-Jun N-terminal kinase inhibition on object recognition memory.Frontiers in behavioral neuroscience · 2022Article
- Special Issue "Molecular Mechanisms of Memory Formation and Modification".International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Memory is not a stable record of experience, but instead is an ongoing process that allows existing memories to be modified with new information through a reconsolidation-dependent updating process. For a previously stable memory to be updated, the memory must first become labile through a process called destabilization. Destabilization is a protein degradation-dependent process that occurs when new information is presented. Following destabilization, a memory becomes stable again through a protein synthesis-dependent process called restabilization. Much work remains to fully characterize the mechanisms that underlie both destabilization and subsequent restabilization, however. In this article, we briefly review the discovery of reconsolidation as a potential mechanism for memory updating. We then discuss the behavioral paradigms that have been used to identify the molecular mechanisms of reconsolidation-dependent memory updating. Finally, we outline what is known about the molecular mechanisms that support the memory updating process. Understanding the molecular mechanisms underlying reconsolidation-dependent memory updating is an important step toward leveraging this process in a therapeutic setting to modify maladaptive memories and to improve memory when it fails.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.