Evidence map›Paper›PMID 32916678›Full record

ReviewJournal of neural engineering2020

Insights into human cognition from intracranial EEG: A review of audition, memory, internal cognition, and causality.

Elizabeth L Johnson, Julia W Y Kam, Athina Tzovara, Robert T Knight

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neural engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Brain dynamics of mental manipulation.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Sleep Modulates Neural Timescales and Spatiotemporal Integration in the Human Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Differential neural mechanisms underlie cortical gating of visual spatial attention mediated by alpha-band oscillations.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Elizabeth L JohnsonHelen Wills Neuroscience Institute, University of California, Berkeley, United States of America.ORCID 0000-0001-5297-5019
Julia W Y KamHelen Wills Neuroscience Institute, University of California, Berkeley, United States of America.
Athina TzovaraHelen Wills Neuroscience Institute, University of California, Berkeley, United States of America.ORCID 0000-0002-7588-1418
Robert T KnightHelen Wills Neuroscience Institute, University of California, Berkeley, United States of America.
University of Bern · CHUniversity of Calgary · CAUniversity of California, Berkeley · USWayne State University · US

Funding

Project 5: ComputationalP50MH109429 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI Robert Thomas Knight · 2017 to 2026
$25.3M
Neural circuit theory and trained recurrent network modeling of rapid learningU19NS107609 · NINDS · UNIVERSITY OF WASHINGTON · PI BUFFALO, ELIZABETH A · 2018 to 2022
$12.6M
Attention, Orientation and the Human Prefrontal CortexR01NS021135 · NINDS · UNIVERSITY OF CALIFORNIA DAVIS · PI Robert Thomas Knight · 1985 to 2026
$6.5M
ATTENTION, ORIENTATION, & THE HUMAN PREFRONTAL CORTEXR37NS021135 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI KNIGHT, ROBERT THOMAS · 2013 to 2019
$3.6M
Measuring Electrical Activity from the Human Brain to Predict Memory Formation and Behavior Across the LifespanR00NS115918 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JOHNSON, ELIZABETH · 2022 to 2024
$843k
Measuring Electrical Activity from the Human Brain to Predict Memory Formation and Behavior Across the LifespanK99NS115918 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JOHNSON, ELIZABETH · 2020 to 2021
$258k
NIMH NIH HHS P50 MH109429NINDS NIH HHS K99 NS115918NINDS NIH HHS R00 NS115918NINDS NIH HHS R01 NS021135NINDS NIH HHS R37 NS021135NINDS NIH HHS U19 NS107609
6 · The paper itself

Abstract

By recording neural activity directly from the human brain, researchers gain unprecedented insight into how neurocognitive processes unfold in real time. We first briefly discuss how intracranial electroencephalography (iEEG) recordings, performed for clinical practice, are used to study human cognition with the spatiotemporal and single-trial precision traditionally limited to non-human animal research. We then delineate how studies using iEEG have informed our understanding of issues fundamental to human cognition: auditory prediction, working and episodic memory, and internal cognition. We also discuss the potential of iEEG to infer causality through the manipulation or 'engineering' of neurocognitive processes via spatiotemporally precise electrical stimulation. We close by highlighting limitations of iEEG, potential of burgeoning techniques to further increase spatiotemporal precision, and implications for future research using intracranial approaches to understand, restore, and enhance human cognition.

Indexed as

ElectrocorticographyElectroencephalographyAnimalsAuditory PerceptionBrainCognitionHumansMemory

Identifiers

PMID32916678
PMCPMC7731730
OpenAlexW3085891723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.