Evidence map›Paper›PMID 32916451›Full record

ArticleDrug and alcohol dependence2020

History of opioid use as a risk factor for current use and mental health consequences among retired National Football League athletes: A 9-year follow-up investigation.

Zachary L Mannes, Eugene M Dunne, Erin G Ferguson, Linda B Cottler, Nicole Ennis

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zachary L MannesDepartment of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, P.O. Box 100165, 1225 Center Drive, Room 3146 Gainesville, FL, 32610-0165, United States. Electronic address: zmannes@ufl.edu.
Eugene M DunneCenters for Behavioral and Preventive Medicine, The Miriam Hospital, CORO Building West, Suite 309, 164 Summit Ave, Providence, RI, 02906, United States; Alpert Medical School, Brown University, Providence, RI, 02906, United States.
Erin G FergusonDepartment of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, P.O. Box 100165, 1225 Center Drive, Room 3146 Gainesville, FL, 32610-0165, United States.
Linda B CottlerDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida P.O. Box 100231, 2004 Mowry Road, Gainesville, FL, 32610, United States.
Nicole EnnisDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Center for Translational Behavioral Science, Tallahassee, FL, 32310, United States.
University of Florida · USBrown University · USFlorida State University · US

Funding

UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
Prescription Drug Misuse, Abuse and DependenceR01DA020791 · NIDA · WASHINGTON UNIVERSITY · PI COTTLER, LINDA B. · 2006 to 2010
$1.9M
Tai Chi intervention to improve chronic pain management for adults with HIVK23AT010099 · NCCIH · TEMPLE UNIV OF THE COMMONWEALTH · PI DUNNE, EUGENE M · 2019 to 2023
$799k
Feasibility of SBIRT for Underserved HIV+ Adults 50+ in Primary Care SettingsK23DA039769 · NIDA · UNIVERSITY OF FLORIDA · PI ENNIS, NICOLE · 2016 to 2020
$769k
NCCIH NIH HHS K23 AT010099NIDA NIH HHS K23 DA039769NIDA NIH HHS R01 DA020791NIDA NIH HHS T32 DA035167
6 · The paper itself

Abstract

backgroundMany retired National Football League (NFL) athletes manage pain with opioids during their playing careers and in retirement, though the longitudinal association between opioid use and health outcomes pertinent to an NFL career are not yet known. This study aimed to assess the relationship between opioid use in 2010 and current use, depressive symptoms, and health related quality of life (HRQoL) among NFL retirees.

methodsFormer NFL athletes from the Retired NFL Players Association initially recruited in 2010 for a study examining risk factors of opioid use and misuse were re-contacted (N = 89) from 2018 to 2019 and administered measures of pain, opioid use, depressive symptoms, and HRQoL. Binomial regression examined the association between 2010 opioid use with current use, moderate-severe depressive symptoms, and average and above HRQoL (physical and mental) while controlling for covariates.

resultsNearly 50 % of retirees using opioids in 2010 currently used. Compared to non-users, retirees who used opioids in 2010 had greater odds of current use (AOR: 3.71, 95 % CI: 1.02-13.56, p = 0.046) and experiencing moderate-severe depressive symptoms (AOR: 5.93, 95 % CI: 1.15-30.54, p = 0.033). Retirees reporting use in 2010 also evidenced lower odds of reporting average or above mental HRQoL (AOR: 0.13, 95 % CI: 0.03-0.67, p = 0.015) compared to non-users.

conclusionsThis study showed that among NFL retirees, early retirement opioid use predicted current use and deleterious effects on mental health, including moderate-severe depressive symptoms approximately nine years later. This investigation further supports the importance of early intervention of pain and opioid use among this population.

Indexed as

Mental HealthAdultAnalgesics, OpioidAthletesFollow-Up StudiesFootballHumansMaleOpioid-Related DisordersPainQuality of LifeRetirementRisk FactorsAnalgesics, OpioidDepressionMental healthNational Football LeaugeNFLOpioid usePain

Identifiers

PMID32916451
PMCPMC7590231
OpenAlexW3082413443

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.