Evidence map›Paper›PMID 32916112›Full record

ArticleCurrent biology : CB2020

PLK1- and PLK4-Mediated Asymmetric Mitotic Centrosome Size and Positioning in the Early Zebrafish Embryo.

Lindsay I Rathbun, Abrar A Aljiboury, Xiaofei Bai, Nicole A Hall, Julie Manikas, Jeffrey D Amack, Joshua N Bembenek, Heidi Hehnly

Open access · hybridAbstract readVideo-Audio Media
In one paragraph

Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Collective effects of cell cleavage dynamics.Frontiers in cell and developmental biology · 2024
    Review
  9. Review
  10. Article
  11. Protein phase separation: new insights into cell division.Acta biochimica et biophysica Sinica · 2023
    Article
  12. Article
  13. Article
  14. Regulation of organelle size and organization during development.Seminars in cell & developmental biology · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lindsay I RathbunSyracuse University, Department of Biology, 107 College Place, Syracuse, NY 13244, USA.
Abrar A AljibourySyracuse University, Department of Biology, 107 College Place, Syracuse, NY 13244, USA.
Xiaofei BaiUniversity of Tennessee, Department of Biochemistry, Cellular and Molecular Biology, 1311 Cumberland Avenue, Knoxville, TN 37916, USA.
Nicole A HallSyracuse University, Department of Biology, 107 College Place, Syracuse, NY 13244, USA.
Julie ManikasSyracuse University, Department of Biology, 107 College Place, Syracuse, NY 13244, USA.
Jeffrey D AmackSUNY Upstate Medical School, Department of Cell and Developmental Biology, 766 Irving Avenue, Syracuse, NY 13210, USA.
Joshua N BembenekUniversity of Tennessee, Department of Biochemistry, Cellular and Molecular Biology, 1311 Cumberland Avenue, Knoxville, TN 37916, USA; University of Michigan Medical School, Department of Molecular, Cellular, Developmental Biology, 1105 North University Avenue, Ann Arbor, MI 48109-1085, USA.
Heidi HehnlySyracuse University, Department of Biology, 107 College Place, Syracuse, NY 13244, USA. Electronic address: hhehnly@syr.edu.
Syracuse University · USSUNY Upstate Medical University · USUniversity of Michigan · USUniversity of Tennessee at Knoxville · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Cell Cycle Regulation of Membrane TraffickingR01GM114471 · NIGMS · WAYNE STATE UNIVERSITY · PI BEMBENEK, JOSHUA NATHANIEL · 2015 to 2024
$2.6M
The relationship between Rab11-endosomes and the centrosome during divisionR01GM127621 · NIGMS · SYRACUSE UNIVERSITY · PI HEHNLY, HEIDI · 2018 to 2022
$1.8M
Mother Centriole Appendages Regulate the AMIS Compartment and Cilogenesis.R00GM107355 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI HEHNLY, HEIDI · 2015 to 2017
$723k
NIGMS NIH HHS R00 GM107355NIGMS NIH HHS R01 GM114471NIGMS NIH HHS R01 GM127621NIH HHS P40 OD010440
6 · The paper itself

Abstract

Factors that regulate mitotic spindle positioning remain unclear within the confines of extremely large embryonic cells, such as the early divisions of the vertebrate embryo, Danio rerio (zebrafish). We find that the mitotic centrosome, a structure that assembles the mitotic spindle [1], is notably large in the zebrafish embryo (246.44 ± 11.93 μm

Indexed as

Embryonic DevelopmentAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCell Cycle ProteinsCell SizeCentrosomeEmbryo, NonmammalianIntravital MicroscopyMicroscopy, ConfocalMitosisPolo-Like Kinase 1Protein Serine-Threonine KinasesProto-Oncogene ProteinsSpindle ApparatusZebrafishCell Cycle ProteinsPolo-Like Kinase 1Protein Serine-Threonine KinasesProto-Oncogene ProteinsZebrafish ProteinsC. eleganscentrosomeembryomicrotubulesmitosisPCMPLK1PLK4spindlezebrafish

Identifiers

PMID32916112
PMCPMC8159022
OpenAlexW3084655197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.