ArticleVeterinary surgery : VS2021
Diagnostic accuracy of optical coherence tomography for assessing surgical margins of canine soft tissue sarcomas in observers of different specialties.
Article in Veterinary surgery : VS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Polarisation-Sensitive Optical Coherence Tomography for Surgical Margin Evaluation and Diagnosis of Excised Canine Cutaneous and Subcutaneous Tumours.Veterinary and comparative oncology · 2026Article
- Biophotonics in veterinary medicine: current clinical applications, translational challenges, and emerging opportunities.Frontiers in veterinary science · 2026Article
- Recurrence and metastasis of cutaneous and subcutaneous tumors following excision with advanced surgical margin assessment.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- Scar revision for incompletely or narrowly excised soft tissue sarcomas in dogs.The Canadian veterinary journal = La revue veterinaire canadienne · 2023Article
- Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumours.Veterinary and comparative oncology · 2022Article
- Article
- The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumours.Veterinary and comparative oncology · 2021Article
Corrections and comments
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Authors and funding
21 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine the diagnostic accuracy of optical coherence tomography (OCT) to assess surgical margins of canine soft tissue sarcoma (STS) and determine the influence of observer specialty and training. STUDY
designBlinded clinical prospective study. ANIMALS: Twenty-five dogs undergoing surgical excision of STS.
methodsIn vivo and ex vivo surgical margins were imaged with OCT after tumor resection. Representative images and videos were used to generate a training presentation and data sets. These were completed by 16 observers of four specialties (surgery, radiology, pathology, and OCT researchers). Images and videos from data sets were classified as cancerous or noncancerous.
resultsThe overall sensitivity and specificity were 88.2% and 92.8%, respectively, for in vivo tissues and 82.5% and 93.3%, respectively, for ex vivo specimens. The overall accurate classification for all specimens was 91.4% in vivo and 89.5% ex vivo. There was no difference in accuracy of interpretation of OCT imaging by observers of different specialties or experience levels.
conclusionUse of OCT to accurately assess surgical margins after STS excision was associated with a high sensitivity and specificity among various specialties. Personnel of all specialties and experience levels could effectively be trained to interpret OCT imaging. CLINICAL SIGNIFICANCE: Optical coherence tomography can be used by personnel of different specialty experience levels and from various specialties to accurately identify canine STS in vivo and ex vivo after a short training session. These encouraging results provide evidence to justify further research to assess the ability of OCT to provide real-time assessments of surgical margins and its applicability to other neoplasms.
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