Evidence map›Paper›PMID 32915558›Full record

ArticleJournal of the American Chemical Society2020

What Makes Thienoguanosine an Outstanding Fluorescent DNA Probe?

Jagannath Kuchlyan, Lara Martinez-Fernandez, Mattia Mori, Krishna Gavvala, Stefano Ciaco, Christian Boudier, Ludovic Richert, Pascal Didier, Yitzhak Tor, Roberto Improta and 1 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Isomorphic Fluorescent Nucleosides.Accounts of chemical research · 2024
    Article
  11. Rationalizing the environment-dependent photophysical behavior of a DNA luminescent probe by classical and non-adiabatic molecular dynamics simulations.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  12. Inherently Emissive Puromycin Analogues for Live Cell Labelling.Angewandte Chemie (International ed. in English) · 2023
    Article
  13. Article
  14. Article
  15. Acipimox inhibits human carbonic anhydrases.Journal of enzyme inhibition and medicinal chemistry · 2022
    Article
  16. Miniaturized Chemical Tags for Optical Imaging.Angewandte Chemie (International ed. in English) · 2022
    Review
  17. Article
  18. Article
  19. A New Variant of Emissive RNA Alphabets.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jagannath KuchlyanLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
Lara Martinez-FernandezDepartamento de Química, Facultad de Ciencias and Institute for Advanced Research in Chemistry (IADCHEM), Universidad Autónoma de Madrid, Campus de Excelencia UAM-CSIC, Cantoblanco, 28049 Madrid, Spain.
Mattia MoriDepartment of Biotechnology, Chemistry, and Pharmacy, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.ORCID 0000-0003-2398-1254
Krishna GavvalaLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
Stefano CiacoLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
Christian BoudierLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
Ludovic RichertLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.
Pascal DidierLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.ORCID 0000-0003-2850-9186
Yitzhak TorDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0358, United States.ORCID 0000-0003-3726-7799
Roberto ImprotaConsiglio Nazionale delle Ricerche, Istituto Biostrutture e Bioimmagini, Via Mezzocannone 16, 80134 Napoli, Italy.ORCID 0000-0003-1004-195X
Yves MélyLaboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France.ORCID 0000-0001-7328-8269

Funding

Fluorescent Nucleosides and OligonucleotidesR01GM069773 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TOR, YITZHAK · 2004 to 2020
$5.0M
NIGMS NIH HHS R01 GM069773
6 · The paper itself

Abstract

Thienoguanosine (

Indexed as

DNADNA ProbesFluorescent DyesGuanosineKineticsMolecular Dynamics SimulationNucleic Acid ConformationSolventsSpectrometry, FluorescenceStructure-Activity RelationshipDNADNA ProbesFluorescent DyesGuanosineSolventsthienoguanosine

Identifiers

PMID32915558
PMCPMC7544670

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.