Evidence map›Paper›PMID 32915505›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins.

Maria Pia Lenza, Iker Oyenarte, Tammo Diercks, Jon Imanol Quintana, Ana Gimeno, Helena Coelho, Ana Diniz, Francesca Peccati, Sandra Delgado, Alexandre Bosch and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Glycoproteins in Viruses.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  12. International journal of molecular sciences · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Integrative Approaches to Study Virus Structures.Sub-cellular biochemistry · 2024
    Review
  17. Review
  18. Article
  19. Review
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Maria Pia LenzaCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Iker OyenarteCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Tammo DiercksCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Jon Imanol QuintanaCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Ana GimenoCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Helena CoelhoUCIBIO, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Ana DinizUCIBIO, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Francesca PeccatiCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Sandra DelgadoCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Alexandre BoschCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Mikel ValleCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Oscar MilletCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Nicola G A AbresciaCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Asís PalazónCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Filipa MarceloUCIBIO, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Gonzalo Jiménez-OsésCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
Jesús Jiménez-BarberoCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.ORCID 0000-0001-5421-8513
Ana ArdáCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
June Ereño-OrbeaCIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia Technology Park, 48162, Derio, Spain.
CIC bioGUNE · ESIkerbasque · ESRede de Química e Tecnologia · PT

Funding

Agencia Estatal de Investigación PGC2018-098996-B-I00Agencia Estatal de Investigación RTI2018-094751-B-C21Agencia Estatal de Investigación RTI2018-095700-B-I00Agencia Estatal de Investigación RTI2018-099592-B-C22Agencia Estatal de Investigación RTI2018-101269-B-I00Agencia Estatal de Investigación SEV-2016-0644European Research Council 788143Fundacao para a Ciencia e a Tecnologia 22161Fundacao para a Ciencia e a Tecnologia IF/00780/2015Fundacao para a Ciencia e a Tecnologia PD/BD/142847/2018Fundacao para a Ciencia e a Tecnologia PTDC/BIA-MIB/31028/2017Fundacao para a Ciencia e a Tecnologia UCIBIO UIDB/04378/2020Mizutani Foundation for Glycoscience 200077
6 · The paper itself

Abstract

The glycan structures of the receptor binding domain of the SARS-CoV2 spike glycoprotein expressed in human HEK293F cells have been studied by using NMR. The different possible interacting epitopes have been deeply analysed and characterized, providing evidence of the presence of glycan structures not found in previous MS-based analyses. The interaction of the RBD

Indexed as

Models, MolecularAngiotensin-Converting Enzyme 2GlycosylationHEK293 CellsHumansLectins, C-TypeNuclear Magnetic Resonance, BiomolecularPolysaccharidesProtein BindingReceptors, CoronavirusSARS-CoV-2Spike Glycoprotein, CoronavirusAngiotensin-Converting Enzyme 2Lectins, C-TypePolysaccharidesReceptors, CoronavirusSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2glycanlectinmolecular recognitionreceptor binding domainSARS-CoV2

Identifiers

PMID32915505
PMCPMC7894318
OpenAlexW3094609706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.