ArticleeLife2020
Neural variability determines coding strategies for natural self-motion in macaque monkeys.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Distributed burst firing mediates optimized cortical encoding of natural self-motion.Science advances · 2026Article
- Vestibular Function Drives Gaze Stability in Locomoting Macaques.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Toward a neuroergonomic understanding of spatial disorientation.Frontiers in physiology · 2026Review
- In vivo neural activity of electrosensory pyramidal cells: Biophysical characterization and phenomenological modeling.PLoS computational biology · 2025Article
- Noisy galvanic vestibular stimulation induces stochastic resonance in vestibular perceptual thresholds assessed efficiently using confidence reports.Experimental brain research · 2024Article
- Review
- Neural populations within macaque early vestibular pathways are adapted to encode natural self-motion.PLoS biology · 2024Article
- Multisensory gaze stabilization in response to subchronic alteration of vestibular type I hair cells.eLife · 2023Article
- Article
- Coding of object location by heterogeneous neural populations with spatially dependent correlations in weakly electric fish.PLoS computational biology · 2023Article
- Neural substrates of perception in the vestibular thalamus during natural self-motion: A review.Current research in neurobiology · 2023Review
- Vestibular perceptual testing from lab to clinic: a review.Frontiers in neurology · 2023Review
- Sensory adaptation mediates efficient and unambiguous encoding of natural stimuli by vestibular thalamocortical pathways.Nature communications · 2022Article
- Imbalance and dizziness caused by unilateral vestibular schwannomas correlate with vestibulo-ocular reflex precision and bias.Journal of neurophysiology · 2022Article
- Neural variability determines coding strategies for natural self-motion in macaque monkeys.eLife · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
We have previously reported that central neurons mediating vestibulo-spinal reflexes and self-motion perception optimally encode natural self-motion (Mitchell et al., 2018). Importantly however, the vestibular nuclei also comprise other neuronal classes that mediate essential functions such as the vestibulo-ocular reflex (VOR) and its adaptation. Here we show that heterogeneities in resting discharge variability mediate a trade-off between faithful encoding and optimal coding via temporal whitening. Specifically, neurons displaying lower variability did not whiten naturalistic self-motion but instead faithfully represented the stimulus' detailed time course, while neurons displaying higher variability displayed temporal whitening. Using a well-established model of VOR pathways, we demonstrate that faithful stimulus encoding is necessary to generate the compensatory eye movements found experimentally during naturalistic self-motion. Our findings suggest a novel functional role for variability toward establishing different coding strategies: (1) faithful stimulus encoding for generating the VOR; (2) optimized coding via temporal whitening for other vestibular functions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.