ArticleeLife2020
Nutrient levels and trade-offs control diversity in a serial dilution ecosystem.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 56 citations in OpenAlex.
- Cross-feeding enables robust coexistence between four bacterial species.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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- The network structure of cross-feeding impacts microbial community diversity under growth-inhibiting stresses.Nature communications · 2026Article
- Mathematical Modelling and Intuition in Microbiology: A Perspective.Environmental microbiology · 2026Review
- Population dynamics of generalist and specialist strategies under feast-famine cycles.PLoS computational biology · 2026Article
- Slow spatial migration can help eradicate cooperative antimicrobial resistance in time-varying environments.PLoS computational biology · 2026Article
- Metabolic blueprints of monocultures enable prediction and design of synthetic microbial consortia.bioRxiv : the preprint server for biology · 2026Article
- Ecological diversification in rapidly evolving populations.bioRxiv : the preprint server for biology · 2025Article
- Coarse-grained model of serial dilution dynamics in synthetic human gut microbiome.PLoS computational biology · 2025Article
- Dynamic coexistence driven by physiological transitions in microbial communities.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Microbial Metabolic Limitations and Their Relationships with Sediment Organic Carbon Across Lake Salinity Gradient in Tibetan Plateau.Microorganisms · 2025Article
- Biodiversity is enhanced by sequential resource utilization and environmental fluctuations via emergent temporal niches.PLoS computational biology · 2024Article
- Formation of a constructed microbial community in a nutrient-rich environment indicates bacterial interspecific competition.mSystems · 2024Article
- Grow now, pay later: When should a bacterium go into debt?Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Resource competition predicts assembly of gut bacterial communities in vitro.Nature microbiology · 2024Article
- Simulated nitrogen deposition and precipitation events alter microbial carbon cycling during early stages of litter decomposition.Sustainable microbiology · 2024Article
- Assessing the Utility of Multiplexed Polymerase Chain Reaction in Detecting Microorganisms Causing Infections in Critically ill Patients.Current microbiology · 2023Article
- Siderophore-mediated iron partition promotes dynamical coexistence between cooperators and cheaters.iScience · 2023Article
- Spatiotemporal ecological chaos enables gradual evolutionary diversification without niches or tradeoffs.eLife · 2023Article
- Modulation of antibiotic effects on microbial communities by resource competition.Nature communications · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Microbial communities feature an immense diversity of species and this diversity is linked to outcomes ranging from ecosystem stability to medical prognoses. Yet the mechanisms underlying microbial diversity are under debate. While simple resource-competition models don't allow for coexistence of a large number of species, it was recently shown that metabolic trade-offs can allow unlimited diversity. Does this diversity persist with more realistic, intermittent nutrient supply? Here, we demonstrate theoretically that in serial dilution culture, metabolic trade-offs allow for high diversity. When a small amount of nutrient is supplied to each batch, the serial dilution dynamics mimic a chemostat-like steady state. If more nutrient is supplied, community diversity shifts due to an 'early-bird' effect. The interplay of this effect with different environmental factors and diversity-supporting mechanisms leads to a variety of relationships between nutrient supply and diversity, suggesting that real ecosystems may not obey a universal nutrient-diversity relationship.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.