Evidence map›Paper›PMID 32914848›Full record

Observational studyBioscience reports2020

Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate.

Giselmo Pinheiro Lopes, Ítalo Patrick Souza Amorim, Bruna de Oliveira de Melo, Carlos Eduardo Campos Maramaldo, Maria Rosa Quaresma Bomfim, Lídio Gonçalves Lima Neto, Matheus Silva Alves, Fabrício Brito Silva, Paulo Vítor Soeiro-Pereira, Angela Falcai

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Prevalence of respiratory viruses in stable and acute asthma: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. The role of virus in nasal inflammation.European journal of medical research · 2025
    Review
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  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giselmo Pinheiro LopesPostgraduate Program in Environment, São Luís, Maranhão, Brazil.
Ítalo Patrick Souza AmorimPostgraduate Program in Environment, São Luís, Maranhão, Brazil.
Bruna de Oliveira de MeloPostgraduate Program in Microbial Biology, CEUMA University, São Luís, Maranhão, Brazil.
Carlos Eduardo Campos MaramaldoPostgraduate Program in Microbial Biology, CEUMA University, São Luís, Maranhão, Brazil.
Maria Rosa Quaresma BomfimPostgraduate Program in Microbial Biology, CEUMA University, São Luís, Maranhão, Brazil.
Lídio Gonçalves Lima NetoPostgraduate Program in Microbial Biology, CEUMA University, São Luís, Maranhão, Brazil.
Matheus Silva AlvesGraduate Program, Ceuma University, São Luís, Maranhão, Brazil.
Fabrício Brito SilvaPostgraduate Program in Environment, São Luís, Maranhão, Brazil.
Paulo Vítor Soeiro-PereiraDepartment of Pathology, Federal University od Maranhão, São Luís, Maranhão, Brazil.
Angela FalcaiPostgraduate Program in Environment, São Luís, Maranhão, Brazil.
Universidade Ceuma · BRUniversidade Federal do Maranhão · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAsthma is a disease that has been associated with the presence of different genetic and socio-environmental factors.

objectiveTo identify and evaluate the seasonality of respiratory syncytial virus (RSV) and human rhinovirus (RV) in asthmatic children and adolescents in tropical climate, as well as to assess the socioeconomic and environmental factors involved.

methodsThe study was conducted in a referral hospital, where a total of 151 children were recruited with a respiratory infection. The International Study of Asthma and Allergies in Childhood (ISAAC) protocol and a questionnaire were applied, and a skin prick test was performed. The nasal swab was collected to detect RV and RSV through molecular assay. National Meteorological Institute (INMET) database was the source of climatic information.

resultsThe socio-environmental characterization of asthmatic children showed the family history of allergy, disturbed sleep at night, dry cough, allergic rhinitis, individuals sensitized to at least one mite. We identified RV in 75% of children with asthma and 66.7% of RSV in children with asthma. There was an association between the presence of RV and the dry season whereas the presence of the RSV was associated with the rainy season. Contributing to these results, a negative correlation was observed between the RSV and the wind speed and the maximum temperature (T. Max) and a positive correlation with precipitation.

conclusionsThe results suggest a high prevalence of RV and RSV in asthmatic children and the seasonality of these viruses were present in different climatic periods. This has significant implications for understanding short- and long-term clinical complications in asthmatic patients.

Indexed as

AsthmaBrazilChildChild, PreschoolCommon ColdFemaleHumansMalePrevalenceRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRhinovirusSeasonsTropical Climateallergyasthmaclimaterespiratory infectionrhinovirusseasonality

Identifiers

PMID32914848
PMCPMC7517263
OpenAlexW3085128728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.