Evidence map›Paper›PMID 32914561›Full record

ArticleActa ophthalmologica2021

Effects of recording sequence on flicker electroretinographics recorded with natural pupils corrected for pupil area.

Asako Sugawara, Kumiko Kato, Ryunosuke Nagashima, Kengo Ikesugi, Masahiko Sugimoto, Hisashi Matsubara, Daphne McCulloch, Mineo Kondo

Open access · hybridAbstract read
In one paragraph

Article in Acta ophthalmologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Intra- and inter-examiner reliability of ERGs recorded with two types of skin electrodes.Documenta ophthalmologica. Advances in ophthalmology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Asako SugawaraDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.
Kumiko KatoDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.ORCID https://orcid.org/0000-0003-4172-3443
Ryunosuke NagashimaDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.
Kengo IkesugiDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.
Masahiko SugimotoDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.
Hisashi MatsubaraDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.
Daphne McCullochSchool of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada.
Mineo KondoDepartment of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.
Mie University · JPUniversity of Waterloo · CA

Funding

Ministry of Education, Culture, Sports, Science and Technology 18H02954
6 · The paper itself

Abstract

backgroundA new handheld electroretinographic (ERG) recording system can record ERGs without mydriasis. However, this RETeval system cannot record ERGs from both eyes simultaneously. Thus, the purpose of this study was to determine whether the sequence of the ERG recordings will alter the results.

methodsWe studied 30 eyes of 30 healthy subjects. The flicker ERGs were recorded with the RETeval system without mydriasis and were elicited by 8, 16 and 32 photopic Td-s. The flicker ERGs were recorded at two sessions. Session 1, the ERGs were recorded from the right eye and then the left eye, and Session 2, ERGs were recorded from the left eye then the right eye. We compared the implicit times, amplitudes and pupil diameters of the right eye between these two sessions.

resultsThe implicit time of the flicker ERGs was significantly shorter (p < 0.001), and the pupil diameters were significantly smaller (p = 0.013) at Session 2 than Session 1 but only for the lower stimulus intensity of eight Td-s. There was a significant correlation of the differences in the implicit times and the differences in the pupil diameter between the two sessions (r = 0.406, p = 0.026).

conclusionsThe results indicate that the implicit times of the fundamental components of RETeval flicker ERGs can be affected by the sequence of recordings for lower stimulus intensities. This was most likely due to the differences of the pupil diameter during the recordings. We recommend that stronger stimuli be used to record the RETeval flicker ERGs to minimize the effects of the sequence of recordings.

Indexed as

AdultFemaleHumansMaleMiddle AgedPhotic StimulationProspective StudiesPupilRetinaVisual AcuityYoung Adultflicker ERGfundamental componentimplicit timespupil diameterRETeval

Identifiers

PMID32914561
PMCPMC8359316
OpenAlexW3086997044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.