Evidence map›Paper›PMID 32914455›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2021

Photochemical Methods for Peptide Macrocyclisation.

Laetitia Raynal, Nicholas C Rose, James R Donald, Christopher D Spicer

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Peptide modificationChemical science · 2026
    Article
  2. Article
  3. Peptide macrocyclisationChemical science · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Photochemical Methods for Peptide Macrocyclisation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laetitia RaynalDepartment of Chemistry, University of York, Heslington, York, YO10 5DD, UK.ORCID http://orcid.org/0000-0001-8183-6763
Nicholas C RoseDepartment of Chemistry, University of York, Heslington, York, YO10 5DD, UK.ORCID http://orcid.org/0000-0003-4839-5737
James R DonaldDepartment of Chemistry, University of York, Heslington, York, YO10 5DD, UK.ORCID http://orcid.org/0000-0002-2176-4902
Christopher D SpicerDepartment of Chemistry, University of York, Heslington, York, YO10 5DD, UK.ORCID http://orcid.org/0000-0001-8787-578X

Funding

Rosetrees Trust A2413
6 · The paper itself

Abstract

Photochemical reactions have been the subject of renewed interest over the last two decades, leading to the development of many new, diverse and powerful chemical transformations. More recently, these developments have been expanded to enable the photochemical macrocyclisation of peptides and small proteins. These constructs benefit from increased stability, structural rigidity and biological potency over their linear counterparts, providing opportunities for improved therapeutic agents. In this review, an overview of both the established and emerging methods for photochemical peptide macrocyclisation is presented, highlighting both the limitations and opportunities for further innovation in the field.

Indexed as

PeptidesCyclizationPhotochemical ProcessesPeptidesmacrocyclisationpeptidesphotochemistry

Identifiers

PMID32914455
PMCPMC7821122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.