Evidence map›Paper›PMID 32914372›Full record

ArticleJournal of gastrointestinal cancer2021

BC032913 as a Novel Antisense Non-coding RNA is Downregulated in Gastric Cancer.

Shiva Behzadi, Behzad Baradaran, Mohammad Ali Hosseinpourfeizi, Narges Dastmalchi, Ali Rajabi, Milad Asadi, Reza Safaralizadeh

Abstract read
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Article in Journal of gastrointestinal cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Expression Level of lncRNA CYTOR in Iranian Cervical Cancer Patients.Reports of biochemistry & molecular biology · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shiva BehzadiDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Behzad BaradaranImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Ali HosseinpourfeiziDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Narges DastmalchiDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Ali RajabiDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Milad AsadiImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza SafaralizadehDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran. safaralizadeh@tabrizu.ac.ir.ORCID http://orcid.org/0000-0002-6970-6998
University of Tabriz · IRTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong non-coding RNAs (lncRNAs) are a subset of non-coding RNAs. Abnormal expression of lncRNAs is associated with the development of cancers including gastric cancer (GC). Increasing evidence in this field reveals that lncRNAs have a key role in biological actions via modulating the expression of genes at various genomic levels. BC032913, as a novel antisense lncRNA, may have a role in GC progression.

objectiveThe very aim of this study was to examine the clinical significance and the functional role of lncRNA BC032913 in GC.

methodsQRT-PCR technique was exerted to survey the expression level of BC032913 in GC tissues and matched adjacent non-tumorous tissues. Furthermore, the association between clinicopathological parameters and the expression level of BC032913 was evaluated.

resultsBC032913 expression was downregulated in cancerous tissues as compared with adjacent non-tumorous tissues (P = 0.0108). Downregulation of BC032913 expression did not demonstrate a significant association with clinicopathological parameters.

conclusionLncRNA BC032913 may be considered as an impressive therapeutic target for GC.

Indexed as

beta-Carotene 15,15'-MonooxygenaseDown-RegulationHumansRNA, Long NoncodingStomach NeoplasmsBCO1 protein, humanbeta-Carotene 15,15'-MonooxygenaseRNA, Long NoncodingClinicopathological parametersGastric cancerLong non-coding RNA BC032913qRT-PCR

Identifiers

PMID32914372
OpenAlexW3084805788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.