Evidence map›Paper›PMID 32914212›Full record

ArticlePflugers Archiv : European journal of physiology2020

Differential modulation of active expiration during hypercapnia by the medullary raphe in unanesthetized rats.

Isabela P Leirão, Daniel B Zoccal, Luciane H Gargaglioni, Glauber S F da Silva

Open access · greenAbstract read
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In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Isabela P LeirãoDepartment of Physiology and Pathology, School of Dentistry of Araraquara (FOAR), São Paulo State University (UNESP), Araraquara, SP, Brazil.
Daniel B ZoccalDepartment of Physiology and Pathology, School of Dentistry of Araraquara (FOAR), São Paulo State University (UNESP), Araraquara, SP, Brazil.
Luciane H GargaglioniDepartment of Animal Morphology and Physiology, College of Agricultural and Veterinary Sciences, São Paulo State University (FCAV-UNESP), Jaboticabal, SP, Brazil.
Glauber S F da SilvaDepartment of Physiology and Biophysics. Institute of Biological Sciences, Federal University of Minas Gerais (ICB/UFMG), Belo Horizonte, MG, Brazil. glauber@icb.ufmg.br.ORCID 0000-0002-6269-7443
Centro Universitário de Araraquara · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Active expiration represents an important mechanism to improve ventilation in conditions of augmented ventilatory demand, such as hypercapnia. While a rostral ventromedullary region, the parafacial respiratory group (pFRG), has been identified as a conditional expiratory oscillator, little is known about how central chemosensitive sites contribute to modulate active expiration under hypercapnia. In this study, we investigated the influence of the medullary raphe in the emergence of phasic expiratory abdominal activity during hypercapnia in unanesthetized adult male rats, in a state-dependent manner. To do so, reverse microdialysis of muscimol (GABA

Indexed as

Exhalation8-Hydroxy-2-(di-n-propylamino)tetralinAbdominal MusclesAnimalsDiaphragmGABA-A Receptor AgonistsHypercapniaMaleMuscimolMuscle ContractionRaphe NucleiRatsRats, WistarSerotonin Receptor AgonistsSleepWakefulness8-Hydroxy-2-(di-n-propylamino)tetralinGABA-A Receptor AgonistsMuscimolSerotonin Receptor AgonistsAbdominal activityBrainstemCentral chemoreceptionSerotonin

Identifiers

PMID32914212
OpenAlexW3084696664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.