ArticleBioactive materials2021
Poly-dopamine, poly-levodopa, and poly-norepinephrine coatings: Comparison of physico-chemical and biological properties with focus on the application for blood-contacting devices.
Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 78 citations in OpenAlex.
- A Heterogeneously structured Mg-Zn laminate alloy for gradient degradation behavior.Bioactive materials · 2026Article
- Polydopamine Nanoparticle-Mediated Precise Near-Infrared Optical Stimulation for Cognitive Enhancement.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- One-Step Confined Polymerization of Catecholamine Biopolymers for the PatternedACS applied materials & interfaces · 2026Article
- Bioinspired catecholamine-derived AuNPs@polynorepinephrine@MWCNT electroactive nanomaterial for real-time monitoring of glucose dynamics.Mikrochimica acta · 2026Article
- Biocompatible molecularly imprinted polynorepinephrine nanoparticles: rational design and one-step reversible immobilization for enhanced protein recognition by surface plasmon resonance.Mikrochimica acta · 2026Article
- Article
- Detection of methyl parathion using a novel oxidized polylevodopa fluorescence nanosensor.Frontiers in chemistry · 2026Article
- Review
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- Visible-Light Photo-Iniferter Polymerization of Molecularly Imprinted Polymers for Direct Integration with Nanotransducers.Small methods · 2025Article
- Construction of pH-responsive hydrogel coatings on titanium surfaces for antibacterial and osteogenic properties.Frontiers in chemistry · 2025Article
- Comparison of the Impact of NaIOACS applied materials & interfaces · 2024Article
- Comparative performance analysis of mussel-inspired polydopamine, polynorepinephrine, and poly-α-methyl norepinephrine in electrochemical biosensors.Mikrochimica acta · 2024Article
- Mussel byssus-inspired dual-functionalization of zirconia dental implants for improved bone integration.Materials today. Bio · 2024Article
- Optimizing the Biocompatibility of PLLA Stent Materials: Strategy with Biomimetic Coating.International journal of nanomedicine · 2024Article
- Poly(levodopa)-Functionalized Polysaccharide Hydrogel Enriched in FeInternational journal of molecular sciences · 2023Article
- Challenge of material haemocompatibility for microfluidic blood-contacting applications.Frontiers in bioengineering and biotechnology · 2023Review
- Bio-macromolecular design roadmap towards tough bioadhesives.Chemical Society reviews · 2022Review
- Polydopamine Copolymers for Stable Drug Nanoprecipitation.International journal of molecular sciences · 2022Article
- Biomimetically Inspired Highly Homogeneous Hydrophilization of Graphene with Poly(l-DOPA): Toward Electroconductive Coatings from Water-Processable Paints.ACS sustainable chemistry & engineering · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thanks to its simplicity, versatility, and secondary reactivity, dopamine self-polymerized coatings (pDA) have been widely used in surface modification of biomaterials, but the limitation in secondary molecular grafting and the high roughness restrain their application in some special scenarios. Therefore, some other catecholamine coatings analog to pDA have attracted more and more attention, including the smoother poly-norepinephrine coating (pNE), and the poly-levodopa coating (pLD) containing additional carboxyl groups. However, the lack of a systematic comparison of the properties, especially the biological properties of the above three catecholamine coatings, makes it difficult to give a guiding opinion on the application scenarios of different coatings. Herein, we systematically studied the physical, chemical, and biological properties of the three catecholamine coatings, and explored the feasibility of their application for the modification of biomaterials, especially cardiovascular materials. Among them, the pDA coating was the roughest, with the largest amount of amino and phenolic hydroxyl groups for molecule grafting, and induced the strongest platelet adhesion and activation. The pLD coating was the thinnest and most hydrophilic but triggered the strongest inflammatory response. The pNE coating was the smoothest, with the best hemocompatibility and histocompatibility, and with the strongest cell selectivity of promoting the proliferation of endothelial cells while inhibiting the proliferation of smooth muscle cells. To sum up, the pNE coating may be a better choice for the surface modification of cardiovascular materials, especially those for vascular stents and grafts, but it is still not widely recognized.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.